Sesn2 - sestrin 2 Gene

Predicted to enable several functions, including GDP-dissociation inhibitor activity; leucine binding activity; and sulfiredoxin activity. Predicted to be involved in several processes, including cellular response to leucine; cellular response to starvation; and regulation of cellular macromolecule biosynthetic process. Predicted to act upstream of or within several processes, including positive regulation of lipophagy; protein kinase B signaling; and regulation of cAMP-dependent protein kinase activity. Predicted to be located in cytoplasm. Predicted to be part of Atg1/ULK1 kinase complex; TORC2 complex; and nucleotide-activated protein kinase complex. Orthologous to human SESN2 (sestrin 2). [provided by Alliance of Genome Resources, Apr 2022]