2. Gene
  3. PALM - paralemmin Gene

PALM - paralemmin Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PALM1

Gene ID: 5064 | Gene type: protein coding

About PALM

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:708,935-748,329 (from NCBI)

This gene has 11 transcripts (splice variants), 235 orthologues and 3 paralogues. Broad expression in fat (RPKM 28.7), brain (RPKM 22.8) and 18 other tissues.

Summary

This gene encodes a member of the paralemmin protein family. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]

PALM Products(2)

mRNA Protein Name
NM_001040134.2 NP_001035224.1 paralemmin-1 isoform 2
NM_002579.3 NP_002570.2 paralemmin-1 isoform 1

PALM Protein Structure

Paralemmin

Paralemmin: Paralemmin (71 - 387)

  • 0
  • 100
  • 200
  • 300
  • 387 a.a.
Protein Preferred Names Protein Names

paralemmin-1

Related Diseases

Diseases Alias
Osteopetrosis, Autosomal Dominant 2

OPTA2

Autosomal Dominant Osteopetrosis 2

Osteopetrosis Autosomal Dominant Type 2

Osteopetrosis, Autosomal Dominant, Type Ii

Albers-Schonberg Osteopetrosis

Autosomal Dominant Albers-Schonberg Disease

Osteopetrosis

Marble Bones, Autosomal Dominant

Osteosclerosis Fragilis Generalisata

Albers-Schonberg Disease, Autosomal Dominant

Autosomal Dominant Osteopetrosis Type Ii

Albers-Schönberg Osteopetrosis

Autosomal Dominant Osteopetrosis Type 2

Marble Disease Autosomal Dominant

Osteopetrosis, Autosomal Dominant, Type 2
Pettigrew Syndrome

PGS

Mrxs5

Mrx59

Mrxs21

X-Linked Intellectual Disability-Dandy-Walker Malformation-Basal Ganglia Disease-Seizures Syndrome

Mental Retardation, X-Linked, Syndromic 5

Mrxsf

Syndromic X-Linked Intellectual Disability 5

Fried Syndrome

Mental Retardation, X-Linked Syndromic 5

Mental Retardation, X-Linked, With Dandy-Walker Malformation, Basal Ganglia Disease, And Seizures

Mental Retardation, X-Linked, Syndromic, Fried Type

Mental Retardation, X-Linked, Syndromic 21

Syndromic X-Linked Mental Retardation 21

Syndromic X-Linked Mental Retardation Fried Type

X-Linked Metal Retardation With Dandy-Walker Malformation, Basal Ganglia Disease, And Seizures

Dandy-Walker Malformation With Intellectual Disability, Basal Ganglia Disease An

Dandy-Walker Malformation With Intellectual Disability, Basal Ganglia Disease And Seizures

X-Linked Syndromic Intellectual Disability 5

X-Linked Intellectual Disability With Dandy-Walker Malformation Basal Ganglia Disease And Seizures

X-Linked Intellectual Disability - Dandy-Walker Malformation - Basal Ganglia Disease - Seizures

X-Linked Intellectual Disability-Hypotonia-Facial Dysmorphism-Aggressive Behavior Syndrome

Mental Retardation, X-Linked Syndromic, Fried Type

Dandy-Walker Malformation With Mental Retardation, Basal Ganglia Disease, And Seizures

Mental Retardation, X-Linked 59
Differentiating Neuroblastoma
Isolated Growth Hormone Deficiency, Type Ii

Ighd Ii

Isolated Growth Hormone Deficiency Type Ii

IGHD2

Growth Hormone Deficiency, Isolated, Type Ii

Congenital Ighd Type Ii

Congenital Isolated Gh Deficiency Type Ii

Congenital Isolated Growth Hormone Deficiency Type Ii

Pituitary Dwarfism Due To Isolated Growth Hormone Deficiency Autosomal Dominant

Growth Hormone Deficiency, Isolated, Autosomal Dominant

Pituitary Dwarfism Due To Isolated Growth Hormone Deficiency, Autosomal Dominant

Autosomal Dominant Isolated Growth Hormone Deficiency

Autosomal Dominant Pituitary Dwarfism Due To Isolated Growth Hormone Deficiency

Isolated Growth Hormone Deficiency Type 2

Growth Hormone Deficiency, Isolated Autosomal Dominant

Growth Hormone Deficiency, Isolated, 2

Growth Hormone Deficiency Isolated Autosomal Dominant
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-P10031A SAR441255 TFA Agonist 99.65% Phase 1
HY-P10031 SAR441255 Agonist / Phase 1
Pre-clinical Phase
Bioactive Molecules (26)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N2041 Myristic acid ≥98.0% Unkown
HY-N0773 Isovitexin Inhibitor 99.82% Unkown
HY-N2041S Myristic acid-d27 98.83% Unkown
HY-135087 Caprylic/Capric Triglyceride 99.89% Unkown
HY-N2041S6 Myristic acid-d5 ≥98.0% Unkown
HY-N2041S3 Myristic acid-d3 98.62% Unkown
HY-W013788 2-Palmitoylglycerol Agonist ≥99.0% Unkown
HY-120634 BMS-929075 Inhibitor / Unkown
HY-133535 PA Janelia Fluor® 646, SE / Unkown
HY-145519 Mu-6S-Palm-β-Glc / Unkown
HY-148701 mono-Pal-MTO / Unkown
HY-148702 di-Pal-MTO / Unkown
HY-157172 MorHap Inhibitor / Unkown
HY-N2041S1 Myristic acid-d2 / Unkown
HY-N2041S2 Myristic acid-13C / Unkown
HY-N2041S4 Myristic acid-13C3 / Unkown
HY-N2041S5 Myristic acid-d1 / Unkown
HY-N2041S7 Myristic acid-d7 / Unkown
HY-N7813 1,2-Dipalmitoyl-3-oleoylglycerol / Unkown
HY-RS10005 PALM Human Pre-designed siRNA Set A / Unkown
HY-RS10006 PALM2AKAP2 Human Pre-designed siRNA Set A / Unkown
HY-RS10007 PALM3 Human Pre-designed siRNA Set A / Unkown
HY-W010736A 1,2-Dipalmitoyl-rac-glycerol / Unkown
HY-W099600 Lauric anhydride / Unkown
HY-W250170 Decyl glucoside / Unkown
HY-D1196 Direct Blue 71 / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PALM VGNC VGNC:32558
Macaca mulatta PALM VGNC VGNC:75751
Felis catus PALM VGNC VGNC:102653
Canis familiaris PALM VGNC VGNC:54980
Rattus norvegicus PALM RGD RGD:620341
Mus musculus PALM MGD MGI:1261814
Others PALM NCBI