Pf4 - platelet factor 4 Gene

Also Known as Cxcl4; Scyb4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56744

Summary

Predicted to enable CXCR3 Chemokine Receptor binding activity; chemokine activity; and heparin binding activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and defense response to protozoan. Located in collagen-containing extracellular matrix. Is expressed in several structures, including blood vessel; bone marrow; central nervous system; liver; and yolk sac. Orthologous to several human genes including PF4 (Platelet Factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Pf4 Products (1)

mRNA Protein Name
NM_019932.5 NP_064316.1 platelet factor 4 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in antimicrobial humoral immune response mediated by antimicrobial peptide IMP
IMP: Inferred from mutant phenotype
23245326 MGI
involved in defense response to protozoan IMP
IMP: Inferred from mutant phenotype
23245326 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet factor 4

  • C-X-C motif chemokine 4

  • chemokine (C-X-C motif) ligand 4

Recombinant Pf4 Proteins

Cat. No. Product Name Accession Purity
HY-P71885 PF-4/CXCL4 Protein, Mouse Q9Z126 (V30-S105) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P78289 PF-4/CXCL4 Protein, Mouse (HEK293, Fc) Q9Z126 (V30-S105) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS17400 Pf4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10355 PF4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10356 PF4V1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23855 Pf4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990391 Anti-CXCL4/PF4 Antibody 95.15% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pf4 NCBI NCBI:5196