NPY2R - neuropeptide Y receptor Y2 Gene

Rattus norvegicus

Gene ID: 66024 | Gene type: protein coding

About NPY2R

Biased expression in Brain (RPKM 13.6), Uterus (RPKM 2.4) and 1 other tissue.

Summary

Enables peptide YY receptor activity. Involved in several processes, including negative regulation of cell communication; regulation of nervous system process; and regulation of secretion. Located in plasma membrane. Is integral component of plasma membrane. Used to study childhood absence epilepsy and mental depression. Biomarker of obesity. Human ortholog(s) of this gene implicated in Huntington's disease; morbid obesity; and obesity. Orthologous to human NPY2R (Neuropeptide Y Receptor Y2). [provided by Alliance of Genome Resources, Apr 2022]

NPY2R Products(1)

mRNA	Protein	Name
NM_023968.1	NP_076458.1	neuropeptide Y receptor type 2

NPY2R Protein Structure

7tmA_NPY2R

0
100
200
300
381 a.a.

Protein Preferred Names

Protein Names

neuropeptide Y receptor type 2

neuropeptide Y-Y2 receptor

neuropeptide Y/peptide YY-Y2 receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-101986A	BIIE-0246 hydrochloride	Antagonist	≥99.0%	Unkown
HY-RS09514	NPY2R Human Pre-designed siRNA Set A		/	Unkown
HY-RS09515	Npy2r Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS09516	NPY2R Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	NPY2R	NCBI	NCBI:4887

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