En1 - engrailed homeobox 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 685360

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in response to cocaine. Located in membrane and nucleus. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human EN1 (engrailed homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

En1 Products (1)

mRNA Protein Name
NM_001398705.1 NP_001385634.1 engrailed homeobox 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to cocaine IEP
IEP: Inferred from expression pattern
17070804 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

engrailed homeobox 1

homeobox protein engrailed-1

  • engrailed 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (65)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-139298 L319 98.0% Unkown
HY-W010639 4-Penten-1-ol 99.99% Unkown
HY-46575 (R)-2-(But-3-en-1-yl)oxirane Control / Unkown
HY-W000981 1-Cyclopentenylboronic acid ≥97.0% Unkown
HY-34409 3-Methyl-2-butenal 97.30% Unkown
HY-43064 (E)-4,4,4-Trifluorobut-2-en-1-ol 98.23% Unkown
HY-43405 (E)-1,3-Di(thiophen-2-yl)prop-2-en-1-one 99.44% Unkown
HY-W015515 L-Citronellol Inhibitor 99.92% Unkown
HY-W015936 (E)-Hex-2-en-1-ol 99.98% Unkown
HY-W038588 2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-en-1-one / Unkown
HY-165707 3-(((Z)-Octadec-9-en-1-yl)oxy)propane-1,2-diyl dioleate / Unkown
HY-W016976 Allyl heptanoate 99.80% Unkown
HY-RS17866 En1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W026038 (Z)-Non-2-en-1-ol 98.00% Unkown
HY-W034462 tert-Butyl (4-aminobut-2-en-1-yl)carbamate hydrochloride 97.0% Unkown
HY-W784556 5'-DMTr-dU(Allylamine-CO-F3)-3'-CE-phosphoramidite / Unkown
HY-139456S 1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole-d3 / Unkown
HY-CE00800A 3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA / Unkown
HY-CE00868 3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA / Unkown
HY-CE01438 6-{(1S,5S)-4-Oxo-5-[(2Z)-pent-2-en-1-yl]cyclopent-2-en-1-yl}hexanoyl-CoA / Unkown
HY-E71488 2-Chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase / Unkown
HY-E71534 2-Glutathionyl-2-methylbut-3-en-1-ol dehydrogenase / Unkown
HY-N12135 15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide / Unkown
HY-N17152 4-Hydroxy-4-methylcyclohex-2-en-1-one / Unkown
HY-N17161 (E)-5-Hydroxy-6-isoprenyl-2-(pent-1-en-1-yl)benzofuran-4-carbaldehyde / Unkown
HY-N17408 (E)-2-(2-Hydroxy-4-methylpheny1)-prop-l-en-1-yl acetate / Unkown
HY-N1873 (E)-4-(3,4-Dimethoxyphenyl)but-3-en-1-ol / Unkown
HY-N2296 (2R,3R)-3,7-Dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one / Unkown
HY-RS04365 EN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W010639S 4-Penten-ol-d9 / Unkown
HY-W017558 (Z)-Non-6-en-1-ol 99.58% Unkown
HY-W075520 N,1-di(pyridin-4-yl)methanimine / Unkown
HY-W127449 trans-2-Nonen-1-ol / Unkown
HY-W243917 4-[[2,3,4,4,6-Pentakis(4-carboxyphenoxy)-1,3,5-triaza-2,4λ5,6-triphosphacyclohex-4-en-1-yl]oxy]benzoicacid / Unkown
HY-W283271 3-Methylcyclohex-2-en-1-ol 98.00% Unkown
HY-W397173 3-Hydroxy-1,3-di(pyridin-4-yl)prop-2-en-1-one / Unkown
HY-W456395 (Z)-4-(Cyclooct-4-en-1-yloxy)-4-oxobutanoic acid / Unkown
HY-W856110 3-(4-Carboxybenzyl)-2-(2-(3-(2-(3-(4-carboxybenzyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)ethylidene)-2-chlorocyclohex-1-en-1-yl)vinyl)-1,1-dimethyl-1H-benzo[e]indol-3-ium bromide / Unkown
HY-Y0400S 2-Bromoethylammonium-d4 bromide / Unkown
HY-Z2289S1 (S)-Ibrutinib-d4 / Unkown
HY-152065S 3,7-Dimethyloct-6-en-1-ol-d2 / Unkown
HY-165708 7(E)-Nonadecenol / Unkown
HY-165708A (Z)-Nonadec-7-en-1-ol / Unkown
HY-165728 (Z)-Octadec-9-en-1-yl methylglycinate / Unkown
HY-165841 11(E)-Octadecenol / Unkown
HY-165883 15(Z)-Tetracosenol / Unkown
HY-165894 Myristoleyl behenate / Unkown
HY-166005 Myristoleyl laurate / Unkown
HY-166006 Myristoleyl myristate / Unkown
HY-403667 2-Cyanoethyl pent-4-en-1-yl diisopropylphosphoramidite / Unkown
HY-N12898 (Z)-Tetradec-7-en-1-ol Activator / Unkown
HY-N9018 4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one / Unkown
HY-RS24335 En1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W007259R (2-Methylprop-1-en-1-yl)benzene (Standard) / Unkown
HY-W008836S (E)-Hex-3-en-1-ol-d2 / Unkown
HY-W108416 (Z)-Tetradec-11-en-1-ol 98.0% Unkown
HY-W142921S Allyl methyl disulfide-d3 / Unkown
HY-W190911 Cyclooct-4-en-1-yl(2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate / Unkown
HY-W249951 Ethyl 2-(4-(((trifluoromethyl)sulfonyl)oxy)cyclohex-3-en-1-yl)acetate / Unkown
HY-W319939 3-(4-Hydroxy-3-methoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one Modulator / Unkown
HY-W654395 Methyl jasmonate-d5 (mixture of diastereomers) / Unkown
HY-W784553 Amino-modifier-C6-dC CEP / Unkown
HY-W784554 5'-DMTr-Amino-modifier-C6-dT-3'-CE-phosphoramidite / Unkown
HY-W838865 11-Dodecenol 98.0% Unkown
HY-W923632 (Z)-Tetradec-9-en-1-ol / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens En1 NCBI NCBI:2019