Nr4a1 - nuclear receptor subfamily 4, group A, member 1 Gene

Also Known as HMR; Nur77; Ngfi-b

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79240

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; Glucocorticoid Receptor binding activity; and protein heterodimerization activity. Involved in several processes, including neurotransmitter secretion involved in regulation of skeletal muscle contraction; response to amphetamine; and response to lipopolysaccharide. Located in nucleus. Used to study Parkinson's disease and chronic kidney disease. Biomarker of mesangial proliferative glomerulonephritis. Orthologous to human NR4A1 (nuclear receptor subfamily 4 group A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Nr4a1 Products (1)

mRNA Protein Name
NM_024388.2 NP_077364.2 nuclear receptor subfamily 4 group A member 1
Protein Preferred Names Protein Names

nuclear receptor subfamily 4 group A member 1

  • Orphan nuclear receptor HMR

  • immediate early gene transcription factor NGFI-B

  • nerve growth factor induced protein I-B

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1624 Teduglutide Activator 99.85% Unkown
HY-P1624A Teduglutide TFA Activator / Unkown

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N2148 Cytosporone B Agonist 99.23% Unkown
HY-112055 DIM-C-pPhOH 98.88% Unkown
HY-159779 NR-V04 Degrader 99.90% Unkown
HY-P2917 Glycerol kinase, microorganism Inhibitor 98.00% Unkown
HY-112056 DIM-C-pPhCO2Me 99.47% Unkown
HY-179528 DIM-3,5-Cl2 99.18% Unkown
HY-160498 Amoitone B Agonist 98.50% Unkown
HY-P1624S1 Teduglutide-Leu(13C6,15N) sodium 96.60% Unkown
HY-RS09550 NR4A1 Human Pre-designed siRNA Set A / Unkown
HY-RS16573 Nr4a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23006 Nr4a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-179112 PROTAC IKKβ/NR4A1 degrader-1 / Unkown
HY-175725 NR4A1 agonist 1 Agonist / Unkown
HY-181588 NR4A agonist-2 Agonist / Unkown
HY-P1624S Teduglutide-Ala(13C3,15N) sodium / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nr4a1 NCBI NCBI:3164