Ica1 - islet cell autoantigen 1 Gene

Also Known as Ica69

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81024

Summary

Enables protein domain specific binding activity. Involved in regulation of protein-containing complex assembly. Located in Golgi apparatus; dendrite; and perinuclear region of cytoplasm. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ICA1 (islet cell autoantigen 1). [provided by Alliance of Genome Resources, Apr 2022]

Ica1 Products (1)

mRNA Protein Name
NM_030844.2 NP_110471.2 islet cell autoantigen 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein domain specific binding IMP
IMP: Inferred from mutant phenotype
18032668 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of protein-containing complex assembly IMP
IMP: Inferred from mutant phenotype
18032668 RGD
Cellular Component GO Annotation Evidence References Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
12682071 RGD
located in Golgi stack IDA
IDA: Inferred from direct assay
12682071 RGD
located in dendrite IDA
IDA: Inferred from direct assay
18032668 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
12682071 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

islet cell autoantigen 1

  • 69 kDa islet cell autoantigen

  • ICAp69

  • islet cell autoantigen 1, 69 kDa

  • islet cell autoantigen p69

  • p69

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-183252 ICA-1S / Unkown
HY-RS06511 ICA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17958 Ica1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24429 Ica1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ica1 NCBI NCBI:3382