Defb1 - defensin beta 1 Gene

Also Known as CDK4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83687

Summary

Predicted to enable CCR6 Chemokine Receptor binding activity; double-stranded DNA binding activity; and identical protein binding activity. Involved in acute inflammatory response and response to testosterone. Predicted to be located in microvesicle and sperm midpiece. Predicted to be extrinsic component of membrane. Predicted to be active in extracellular space. Biomarker of obesity and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and lung disease. Orthologous to human DEFB1 (defensin beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Defb1 Products (1)

mRNA Protein Name
NM_031810.2 NP_113998.1 beta-defensin 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to testosterone IEP
IEP: Inferred from expression pattern
12533413 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-defensin 1

  • BD-1

  • rBD-1

Recombinant Defb1 Proteins

Cat. No. Product Name Accession Purity
HY-P7134 BD-1 Protein, Rat O89117 (D33-S69) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W074890 Palmitoylglycine Modulator 99.84% Unkown
HY-RS03678 DEFB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18060 Defb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24535 Defb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Defb1 NCBI NCBI:1672