STX7 - syntaxin 7 Gene

Homo sapiens

Gene ID: 8417 | Gene type: protein coding

About STX7

Cytogenetic location: 6q23.2 Genomic coordinates (GRCh38): 6:132,445,867-132,513,472 (from NCBI)

This gene has 4 transcripts (splice variants), 210 orthologues and 12 paralogues. Ubiquitous expression in lymph node (RPKM 31.8), spleen (RPKM 19.7) and 24 other tissues.

Summary

The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the ordered fusion of endosomes and lysosomes with the phagosome. [provided by RefSeq, May 2016]

STX7 Products(4)

mRNA	Protein	Name
NM_001326578.2	NP_001313507.1	syntaxin-7 isoform a
NM_001326579.2	NP_001313508.1	syntaxin-7 isoform a
NM_001326580.2	NP_001313509.1	syntaxin-7 isoform b
NM_003569.3	NP_003560.2	syntaxin-7 isoform a

STX7 Protein Structure

Syntaxin_2

SNARE

0
100
200
261 a.a.

Protein Preferred Names

Protein Names

syntaxin-7

Recombinant STX7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71024	STX7 Protein, Human (HEK293, His)	O15400 (S2-L238)	≥95%
HY-P73621	Syntaxin-7 Protein, Human (HEK293, His)	O15400 (S2-L238)	≥95%

Related Diseases

Diseases

Alias

Neuronal Migration Disorders

Abnormality Of Neuronal Migration	Malformations Of Cortical Development, Group Ii
Neuronal Dysmigration Syndromes

Hemophagocytic Lymphohistiocytosis, Familial, 4

Familial Hemophagocytic Lymphohistiocytosis 4	FHL4
Hplh4	Hlh4
Lymphohistiocytosis, Hemophagocytic, Familial, Type 4

Hermansky-Pudlak Syndrome

Hps	Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells
Hermanski-Pudlak Syndrome	Hermansky Pudlak Syndrome
Platelet Storage Pool Deficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13987	STX7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	STX7	VGNC	VGNC:46958
Macaca mulatta	STX7	VGNC	VGNC:78047
Bos taurus	STX7	VGNC	VGNC:35443
Rattus norvegicus	STX7	RGD	RGD:619747
Mus musculus	STX7	MGD	MGI:1858210
Felis catus	STX7	VGNC	VGNC:102526
Others	STX7	NCBI