Rab14 - RAB14, member RAS oncogene family Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 94197

Summary

Predicted to enable GTPase activity; guanyl ribonucleotide binding activity; and Myosin V binding activity. Involved in apical protein localization; body fluid secretion; and regulation of protein localization. Located in several cellular components, including Golgi stack; apical plasma membrane; and cytoplasmic vesicle. Is anchored component of synaptic vesicle membrane. Orthologous to human RAB14 (RAB14, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab14 Products (1)

mRNA Protein Name
NM_053589.2 NP_446041.2 ras-related protein Rab-14

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18332131 RGD
Biological Process GO Annotation Evidence References Source
involved in apical protein localization IDA
IDA: Inferred from direct assay
18429929 RGD
involved in body fluid secretion IMP
IMP: Inferred from mutant phenotype
18332131 RGD
involved in regulation of protein localization IDA
IDA: Inferred from direct assay
18429929 RGD
involved in regulation of protein localization IMP
IMP: Inferred from mutant phenotype
18701652 RGD
Cellular Component GO Annotation Evidence References Source
located in Golgi stack IDA
IDA: Inferred from direct assay
15004230 RGD
located in alveolar lamellar body IDA
IDA: Inferred from direct assay
18332131 RGD
located in apical plasma membrane IDA
IDA: Inferred from direct assay
18429929 RGD
located in cytosol IDA
IDA: Inferred from direct assay
15004230 RGD
located in early endosome IDA
IDA: Inferred from direct assay
15004230 RGD
located in late endosome IDA
IDA: Inferred from direct assay
15004230 RGD
located in lysosome IDA
IDA: Inferred from direct assay
15004230 RGD
located in nuclear outer membrane-endoplasmic reticulum membrane network IDA
IDA: Inferred from direct assay
15004230 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
15004230 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
15004230 RGD
located in rough endoplasmic reticulum IDA
IDA: Inferred from direct assay
15004230 RGD
is active in synaptic vesicle membrane EXP
EXP: Inferred from Experiment
20926670 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
20926670 RGD
is active in synaptic vesicle membrane IMP
IMP: Inferred from mutant phenotype
20926670 RGD
located in trans-Golgi network transport vesicle IDA
IDA: Inferred from direct assay
15004230 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-14

  • GTPase Rab14

Rab14 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Rab14 P61107 NISCH Homo sapiens Q9Y2I1
Pull Down
23386062
Cross
Rab14 P61107 NISCH Homo sapiens Q9Y2I1
CoIP
23386062
Cross
Rab14 P61107 NISCH Homo sapiens Q9Y2I1
IF
23386062
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11523 RAB14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab14 NCBI NCBI:51552