2. GPCR/G Protein
  3. GCGR
  4. GLP-1 receptor agonist 3

GLP-1 receptor agonist 3 (compound (R)-4A-1) is a GLP-1 receptor agonist (WO2018109607A1), used for diabetes research. compound (S)-4A-1 shows EC50s of 1.1 nM and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively.

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GLP-1 receptor agonist 3 Chemical Structure

GLP-1 receptor agonist 3 Chemical Structure

CAS No. : 2230200-09-4

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GLP-1 receptor agonist 3 Related Antibodies

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Description

GLP-1 receptor agonist 3 (compound (R)-4A-1) is a GLP-1 receptor agonist (WO2018109607A1), used for diabetes research. compound (S)-4A-1 shows EC50s of 1.1 nM and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively[1].

IC50 & Target

EC50: 1.1 nM (GLP-1 receptor, in Clone H6 cell lines assay) and 13 nM (GLP-1 receptor, in Clone C6 cell lines assay)[1]
Molecular Weight

555.60

Formula

C31H30FN5O4
CAS No.
SMILES

O=C(C1=CC=C2N=C(CN3CCC(C4=NC(OCC5=CC=C(C#N)C=C5F)=CC=C4)CC3)N(C[C@@H]6OCC6)C2=C1)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GLP-1 receptor agonist 3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GLP-1 receptor agonist 32230200-09-4GCGRGlucagon ReceptorInhibitorinhibitorinhibit

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