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Cat. No.: HY-W071581

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Glucocorticoid receptor activator 1

Glucocorticoid receptor activator 1 (compound A) is a phenyl aziridine precursor and an activator of the glucocorticoid receptor (GR). Glucocorticoid receptor activator 1 down-modulates TNF-induced pro-inflammatory gene expression by activating GR and can be utilized in inflammation research.

For research use only. We do not sell to patients.

CAS No.: 14593-25-0
Formula: C₁₁H₁₅Cl₂NO₂
Molecular Weight:264.15

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Glucocorticoid receptor activator 1 Chemical Structure

CAS No.: 14593-25-0

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Description

Chemical Information

CAS No. 14593-25-0
Molecular Weight 264.15
Formula C₁₁H₁₅Cl₂NO₂
SMILES

CNCC(C1=CC=C(OC(C)=O)C=C1)Cl.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. De Bosscher K, et al. A fully dissociated compound of plant origin for inflammatory gene repression. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15827-32. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Glucocorticoid receptor activator 1

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Glucocorticoid receptor activator 1

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