Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal
Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal, a glucocorticoid receptor agonist, is a drug-linker conjugate for ADC. Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal can be used to synthesize the anti-CD40 antibody agent conjugates (WO2019106608A1; example 9).
For research use only. We do not sell to patients.
- CAS No.: 2345732-83-2
- Formula: C46H50N3O15P
- Molecular Weight:915.87
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 2345732-83-2
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Appearance Solid
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Molecular Weight 915.87
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Formula C46H50N3O15P
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Color White to off-white
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SMILES
O=P(O)(O)OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@@H](C6=CC=C(C=C6)CC7=CC(NC([C@H](CCC(O)=O)NC(CN8C(C=CC8=O)=O)=O)=O)=CC=C7)O2)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : 250 mg/mL (272.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0919 mL | 5.4593 mL | 10.9186 mL | 27.2965 mL |
| 5 mM | 0.2184 mL | 1.0919 mL | 2.1837 mL | 5.4593 mL | |
| 10 mM | 0.1092 mL | 0.5459 mL | 1.0919 mL | 2.7296 mL | |
| 15 mM | 0.0728 mL | 0.3640 mL | 0.7279 mL | 1.8198 mL | |
| 20 mM | 0.0546 mL | 0.2730 mL | 0.5459 mL | 1.3648 mL | |
| 25 mM | 0.0437 mL | 0.2184 mL | 0.4367 mL | 1.0919 mL | |
| 30 mM | 0.0364 mL | 0.1820 mL | 0.3640 mL | 0.9099 mL | |
| 40 mM | 0.0273 mL | 0.1365 mL | 0.2730 mL | 0.6824 mL | |
| 50 mM | 0.0218 mL | 0.1092 mL | 0.2184 mL | 0.5459 mL | |
| 60 mM | 0.0182 mL | 0.0910 mL | 0.1820 mL | 0.4549 mL | |
| 80 mM | 0.0136 mL | 0.0682 mL | 0.1365 mL | 0.3412 mL | |
| 100 mM | 0.0109 mL | 0.0546 mL | 0.1092 mL | 0.2730 mL |
Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal Related Classifications
HY-400878 Related Classifications
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