1. GPCR/G Protein Neuronal Signaling
  2. GPR55
  3. GPR55 agonist 3

GPR55 agonist 3 (Compound 26) is a GPR55 agonist (EC50: 0.239 nM, and 1.76 nM for hGPR55 and rGPR55). GPR55 agonist 3 induces β-arrestin recruitment to human GPR55 (EC50: 6.2 nM).

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GPR55 agonist 3

GPR55 agonist 3 화학구조

CAS No. : 3006105-44-5

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
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500 mg   견적 받기  

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제품 설명

GPR55 agonist 3 (Compound 26) is a GPR55 agonist (EC50: 0.239 nM, and 1.76 nM for hGPR55 and rGPR55). GPR55 agonist 3 induces β-arrestin recruitment to human GPR55 (EC50: 6.2 nM)[1].

분자량

376.35

화학식

C19H16F4N4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

FC(F)(F)CC1=CN=CC(C2=CN=C(N[C@@H](C3=CC=C(F)C=C3)C)C=N2)=C1

선적

Room temperature in continental US; may vary elsewhere.

보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 250 mg/mL (664.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6571 mL 13.2855 mL 26.5710 mL
5 mM 0.5314 mL 2.6571 mL 5.3142 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6571 mL 13.2855 mL 26.5710 mL 66.4275 mL
5 mM 0.5314 mL 2.6571 mL 5.3142 mL 13.2855 mL
10 mM 0.2657 mL 1.3286 mL 2.6571 mL 6.6428 mL
15 mM 0.1771 mL 0.8857 mL 1.7714 mL 4.4285 mL
20 mM 0.1329 mL 0.6643 mL 1.3286 mL 3.3214 mL
25 mM 0.1063 mL 0.5314 mL 1.0628 mL 2.6571 mL
30 mM 0.0886 mL 0.4429 mL 0.8857 mL 2.2143 mL
40 mM 0.0664 mL 0.3321 mL 0.6643 mL 1.6607 mL
50 mM 0.0531 mL 0.2657 mL 0.5314 mL 1.3286 mL
60 mM 0.0443 mL 0.2214 mL 0.4429 mL 1.1071 mL
80 mM 0.0332 mL 0.1661 mL 0.3321 mL 0.8303 mL
100 mM 0.0266 mL 0.1329 mL 0.2657 mL 0.6643 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
GPR55 agonist 3
Cat. No.:
HY-156107
수량:
MCE Japan Authorized Agent: