2. Epigenetics
  3. MicroRNA
  4. hsa-let-7a-5p agomir

hsa-let-7a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

For research use only. We do not sell to patients.

RNA, (UGAGGUAGUAGGUUGUAUAGUU), complex with RNA, (CUAUACAACCUACUACCUCANN) (1:1) (with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification)

hsa-let-7a-5p agomir Chemical Structure

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5 nmol USD 225 Get quote 1-2 weeks 1-2 weeks
20 nmol USD 560 Get quote 1-2 weeks 1-2 weeks
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Based on 1 publication(s) in Google Scholar

Other Forms of hsa-let-7a-5p agomir:

hsa-let-7a-5p agomir Related Antibodies

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Description

hsa-let-7a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

Molecular Weight

15089.35

miRBase Accession Number
Mature miRNA Sequence

UGAGGUAGUAGGUUGUAUAGUU

Stem-loop ID

hsa-let-7a-1

Stem-loop Sequence

UGGGAUGAGGUAGUAGGUUGUAUAGUUUUAGGGUCACACCCACCACUGGGAGAUAACUAUACAAUCUACUGUCUUUCCUA

Species

Human, Mouse, Rat, Caenorhabditis elegans, Alligator mississippiensis, Anolis carolinensis, Ascaris suum, Astatotilapia burtoni, Bovine, Branchiostoma belcheri, Branchiostoma floridae, Brugia malayi, Caenorhabditis brenneri, Caenorhabditis briggsae, Caenorhabditis remanei, Callithrix jacchus, Chicken, Chrysemys picta, Columba livia, Cricetulus griseus, Cyprinus carpio, Dasypus novemcinctus, Daubentonia madagascariensis, Dog, Fugu rubripes, Gadus morhua, Goat, Guinea pig, Heligmosomoides polygyrus, Horse, Ictalurus punctatus, Lottia gigantea, Metriaclima zebra, Microcebus murinus, Monodelphis domestica, Neolamprologus brichardi, Nomascus leucogenys, Ophiophagus hannah, Oreochromis niloticus, Oryzias latipes, Otolemur garnettii, Pan paniscus, Pan troglodytes, Papio hamadryas, Parasteatoda tepidariorum, Petromyzon marinus, Pig, Pongo pygmaeus, Pristionchus pacificus, Pteropus alecto, Pundamilia nyererei, Python bivittatus, Rabbit, Rhesus monkey, Saccoglossus kowalevskii, Saimiri boliviensis, Salmo salar, Sheep, Taeniopygia guttata, Tetraodon nigroviridis, Xenopus laevis, Xenopus tropicalis, Zebrafish

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
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hsa-let-7a-5p agomir Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hsa-let-7a-5p agomirMicroRNAmiRNAInhibitorinhibitorinhibit

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