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Cat. No.: HY-180396

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Ikarisoside B

Ikarisoside B is a potent and selective Organic cation transporter 1 (OCT1) inhibitor with an IC₅₀ of 11.18 μM. Ikarisoside B shows selectivity over OCT2 (IC₅₀ = 56.54 μM). Ikarisoside B can be used for the research of metabolic disease.

For research use only. We do not sell to patients.

CAS No.: 113558-10-4
Formula: C₃₂H₃₈O₁₅
Molecular Weight:662.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Ikarisoside B Chemical Structure

CAS No.: 113558-10-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

OCT1

11.18 μM (IC₅₀)

OCT2

56.54 μM (IC₅₀)

In Vitro

Ikarisoside B (up to 250 μM; 12 h) shows no cytotoxicity in HEK-EV, HEK-OCT1 and HEK-OCT2 cells up to 250 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

HEK-EV, HEK-OCT1 and HEK-OCT2 cells
Concentration:

up to 250 μM
Incubation Time:

12 h
Result:

Exhibited no cytotoxicity in HEK-EV, HEK-OCT1 and HEK-OCT2 cells up to 250 μM, with cell viability > 90%.
Showed 100% cell survival rate in HEK-EV, HEK-OCT1 and HEK-OCT2 cells.

Chemical Information

CAS No. 113558-10-4
Molecular Weight 662.64
Formula C₃₂H₃₈O₁₅
SMILES

O(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2CC=C(C)C)C3=CC=C(O)C=C3)[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@@H](O)[C@H](C)O4
Structure Classification
- Flavonoids
- Flavonols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bi Y, et al. Selective Inhibition of Organic Cation Transporter 1 by Benzoylpaeoniflorin Attenuates Hepatic Lipid Accumulation through AMPK Activation. J Nat Prod. 2023;86(1):191-198. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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