Ipatasertib-NH2 dihydrochloride
Ipatasertib-NH2 dihydrochloride is a ligand for target protein AKT for PROTAC (INY-03-041). INY-03-041 is composed of Ipatasertib-NH2, a ten-hydrocarbon linker, and a CRBN ligand Lenalidomide for E3 ubiquitin ligase.
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- No. CAS: 1001264-73-8
- Fòrmula: C21H28Cl3N5O2
- Peso molecular:488.84
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1001264-73-8
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Peso molecular 488.84
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Fòrmula C21H28Cl3N5O2
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SMILES
C[C@H]1C2=C(N3CCN(CC3)C([C@@H](C4=CC=C(C=C4)Cl)CN)=O)N=CN=C2[C@@H](C1)O.Cl.Cl
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Synonyms
GDC-0068-NH2 dihydrochloride; RG7440-NH2 dihydrochloride
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ipatasertib-NH2 dihydrochloride Related Classifications
HY-130988A Related Classifications
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