1. Epigenetics
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. JAK
  3. JAK-IN-5 hydrochloride

JAK-IN-5 hydrochloride 

Cat. No.: HY-111471A Purity: 99.54%
Handling Instructions

JAK-IN-5 hydrochloride is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.

For research use only. We do not sell to patients.

JAK-IN-5 hydrochloride Chemical Structure

JAK-IN-5 hydrochloride Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 652 In-stock
Estimated Time of Arrival: December 31
5 mg USD 580 In-stock
Estimated Time of Arrival: December 31
10 mg USD 850 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1900 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2800 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Based on 1 publication(s) in Google Scholar

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Description

JAK-IN-5 hydrochloride is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283[1].

IC50 & Target

JAK[1].

Molecular Weight

511.03

Formula

C₂₇H₃₂ClFN₆O

SMILES

CN1CCC(N2CC(N=C(C3=NNC4=C3C=CC(C5=C(CC)C=C(O)C(F)=C5)=C4)N6)=C6CC2)CC1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

Methanol : 10 mg/mL (19.57 mM; ultrasonic and adjust pH to 7 with NaOH)

DMSO : 5 mg/mL (9.78 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9568 mL 9.7842 mL 19.5683 mL
5 mM 0.3914 mL 1.9568 mL 3.9137 mL
10 mM 0.1957 mL 0.9784 mL 1.9568 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

JAK-IN-5JAKJanus kinaseInhibitorinhibitorinhibit

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Product Name:
JAK-IN-5 hydrochloride
Cat. No.:
HY-111471A
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