AcrB-IN-1
AcrB-IN-1 (Compound H6) is a potent AcrB inhibitor. AcrB-IN-1 can be used for the reversal of bacterial multidrug resistance.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2890177-82-7
- 分子式: C32H39N3O4
- 分子量:529.67
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
AcrB-IN-1 (Compound H6) is able to reduce the MIC value of tested antibacterial (Erythromycin HY-B0220, Levofloxacin HY-B0330, Minocycline HY-17412A) at sub-MIC concentrations (8-128 μg/mL) against the Escherichia coli strain BW25113[1].
AcrB-IN-1 (64 μg/mL) is shown to not disrupt the bacterial inner membrane[1].
AcrB-IN-1 completely abolishes the Nile Red (a known substrate of AcrB) efflux at a concentration of 50 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2890177-82-7
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分子量 529.67
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分子式 C32H39N3O4
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SMILES
CC1(C)CCC2=C(O1)C3=C(C=C2C(N4CCOCC4)=O)C(OCCN5CCN(C6=CC=CC=C6)CC5)=CC=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)