AT-1015
AT-1015 is a selective and orally active 5-HT2A serotonin receptor antagonist. AT-1015 exhibits antithrombotic effect. AT-1015 prolongs the time needed to occlusion of the artery with thrombus. AT-1015 impairs platelet aggregation and vasoconstriction.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 190508-48-6
- 分子式: C29H36ClN3O3
- 分子量:510.07
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
5-HT Receptor アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 190508-48-6
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分子量 510.07
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分子式 C29H36ClN3O3
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SMILES
O=C(C1CCN(C=O)CC1)NCCN2CC/C(CC2)=C3C4=CC=CC=C4C=CC5=CC=CC=C/35.O.Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Hiatt, W. R., et al., (2004). Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacy. Vascular medicine (London, England), 9(1), 18-25. [Content Brief]
[2]. Kihara, H., et al., (2001). Antithrombotic activity of AT-1015, a potent 5-HT(2A) receptor antagonist, in rat arterial thrombosis model and its effect on bleeding time. European journal of pharmacology, 433(2-3), 157-162. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)