Clovoxamine
Clovoxamine (DU23811) (Compound 35) has binding affinity for serotonin transporter (SERT) (Ki: 61 nM). Clovoxamine is a 5-HT and norepinephrine reuptake (NE) re-uptake inhibitor. Clovoxamine is an antidepressant.
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- CAS 番号: 54739-19-4
- 分子式: C14H21ClN2O2
- 分子量:284.78
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
5-HT Receptor アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 54739-19-4
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分子量 284.78
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分子式 C14H21ClN2O2
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SMILES
COCCCC/C(C1=CC=C(C=C1)Cl)=N/OCCN
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別名
DU23811
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Staroń J, et al. Tuning the activity of known drugs via the introduction of halogen atoms, a case study of SERT ligands - Fluoxetine and fluvoxamine. Eur J Med Chem. 2021 Aug 5;220:113533. [Content Brief]
[2]. Saletu B, et al. Clovoxamine and fluvoxamine-2 biogenic amine re-uptake inhibiting antidepressants: quantitative EEG, psychometric and pharmacokinetic studies in man. J Neural Transm. 1980;49(1-2):63-86. [Content Brief]
[3]. de Jong GJ. The use of a pre-column for the direct high-performance liquid chromatographic determination of the anti-depressants clovoxamine and fluvoxamine in plasma. J Chromatogr. 1980 Aug 8;183(2):203-11. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)