TMEM219 - transmembrane protein 219 Gene

Also Known as IGFBP-3R

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 124446

About TMEM219

This gene has 8 transcripts (splice variants), 166 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 42.5), small intestine (RPKM 28.6) and 25 other tissues.

Summary

Predicted to be involved in apoptotic process. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM219 Products (5)

mRNA Protein Name
NM_001083613.2 NP_001077082.1 insulin-like growth factor-binding protein 3 receptor isoform 1 precursor
NM_001369688.1 NP_001356617.1 insulin-like growth factor-binding protein 3 receptor isoform 1 precursor
NM_001369689.1 NP_001356618.1 insulin-like growth factor-binding protein 3 receptor isoform 2 precursor
NM_001369690.1 NP_001356619.1 insulin-like growth factor-binding protein 3 receptor isoform 3 precursor
NM_194280.4 NP_919256.1 insulin-like growth factor-binding protein 3 receptor isoform 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
20353938 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM219 Protein Structure

TMEM219

TMEM219: Transmembrane 219 (10 - 175)

  • 0
  • 100
  • 200
  • 240 a.a.
Protein Preferred Names Protein Names

insulin-like growth factor-binding protein 3 receptor

  • testicular tissue protein Li 203

TMEM219 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
TMEM219 Q86XT9 IL13RA2 Homo sapiens Q14627
Anti Bait CoIP
29427412
Intra
TMEM219 Q86XT9 IGFBP3 Homo sapiens P17936
Solid Phase Assay
20353938
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant TMEM219 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P77962 TMEM219/IGFBP-3R Protein, Human (HEK293, Fc) Q86XT9 (S39-R204) ≥ 95%, as determined by Bis-Tris PAGE.

関連疾患

Diseases Alias
Hermansky-Pudlak Syndrome

  • Hps

  • Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

  • Hermanski-Pudlak Syndrome

  • Hermansky Pudlak Syndrome

  • Platelet Storage Pool Deficiency
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS14700 TMEM219 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19096 Tmem219 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus TMEM219 RGD RGD:1560566
Bos taurus TMEM219 VGNC VGNC:36041
Mus musculus TMEM219 MGD MGI:1915992
Canis familiaris TMEM219 VGNC VGNC:47535
Felis catus TMEM219 VGNC VGNC:66315
Macaca mulatta TMEM219 VGNC VGNC:99618
Others TMEM219 NCBI