COL8A1 - collagen type VIII alpha 1 chain Gene

Also Known as C3orf7

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 1295

About COL8A1

Cytogenetic location: 3q12.1 Genomic coordinates (GRCh38): 3:99,638,594-99,799,217 (from NCBI)

This gene has 9 transcripts (splice variants), 239 orthologues and 23 paralogues. Biased expression in urinary bladder (RPKM 16.8), lung (RPKM 16.6) and 13 other tissues.

Summary

This gene encodes one of the two alpha chains of type VIII Collagen. The gene product is a short chain Collagen and a major component of the basement membrane of the corneal endothelium. The type VIII Collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Dec 2011]

COL8A1 Products (2)

mRNA	Protein	Name
NM_001850.5	NP_001841.2	collagen alpha-1(VIII) chain precursor
NM_020351.4	NP_065084.2	collagen alpha-1(VIII) chain precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	参考文献	由来
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

Biological Process GO Annotation	Evidence	参考文献	由来
involved in endodermal cell differentiation	IEP IEP: Inferred from expression pattern	23154389	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

COL8A1 Protein Structure

Collagen

C1q

0
200
400
600
744 a.a.

Protein Preferred Names	Protein Names
collagen alpha-1(VIII) chain	cell proliferation-inducing protein 41

COL8A1 Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	COL8A1	P27658	KRT40	Homo sapiens	Q6A162	Validated Y2H	25416956
Intra	COL8A1	P27658	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	25416956
Intra	COL8A1	P27658	KRTAP10-8	Homo sapiens	P60410	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP10-8	Homo sapiens	P60410	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP10-8	Homo sapiens	P60410	Validated Y2H	25416956
Intra	COL8A1	P27658	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP10-7	Homo sapiens	P60409	Y2H Array	25416956
Intra	COL8A1	P27658	RGS20	Homo sapiens	O76081-6	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	RGS20	Homo sapiens	O76081-6	Y2H Array	32296183
Intra	COL8A1	P27658	CREB5	Homo sapiens	Q02930-3	Y2H Array	25416956
Intra	COL8A1	P27658	CREB5	Homo sapiens	Q02930-3	Validated Y2H	32296183
Intra	COL8A1	P27658	SP4	Homo sapiens	Q02446	Validated Y2H	25416956
Intra	COL8A1	P27658	KRTAP13-3	Homo sapiens	Q3SY46	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP13-3	Homo sapiens	Q3SY46	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP13-3	Homo sapiens	Q3SY46	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP19-7	Homo sapiens	Q3SYF9	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP19-7	Homo sapiens	Q3SYF9	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP19-7	Homo sapiens	Q3SYF9	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP5-6	Homo sapiens	Q6L8G9	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP5-6	Homo sapiens	Q6L8G9	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP5-6	Homo sapiens	Q6L8G9	Y2H Array	32296183
Intra	COL8A1	P27658	ZNF774	Homo sapiens	Q6NX45	Validated Y2H	32296183
Intra	COL8A1	P27658	ZNF774	Homo sapiens	Q6NX45	Y2H Array	32296183
Intra	COL8A1	P27658	ZNF774	Homo sapiens	Q6NX45	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	SPMIP6	Homo sapiens	Q8NCR6	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	SPMIP6	Homo sapiens	Q8NCR6	Y2H Array	32296183
Intra	COL8A1	P27658	SPMIP6	Homo sapiens	Q8NCR6	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP9-3	Homo sapiens	Q9BYQ3	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP9-3	Homo sapiens	Q9BYQ3	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP9-3	Homo sapiens	Q9BYQ3	Y2H Array	32296183
Intra	COL8A1	P27658	KRT82	Homo sapiens	Q9NSB4	Validated Y2H	32296183
Intra	COL8A1	P27658	KRT82	Homo sapiens	Q9NSB4	Y2H Array	32296183
Intra	COL8A1	P27658	KRT82	Homo sapiens	Q9NSB4	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRT37	Homo sapiens	O76014	Y2H Array	32296183
Intra	COL8A1	P27658	KRT37	Homo sapiens	O76014	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP19-5	Homo sapiens	Q3LI72	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP19-5	Homo sapiens	Q3LI72	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP19-5	Homo sapiens	Q3LI72	Validated Y2H	32296183
Intra	COL8A1	P27658	KLHL20	Homo sapiens	Q9BS75	Validated Y2H	32296183
Intra	COL8A1	P27658	KLHL20	Homo sapiens	Q9BS75	Y2H Array	32296183
Intra	COL8A1	P27658	KLHL20	Homo sapiens	Q9BS75	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KPRP	Homo sapiens	Q5T749	Validated Y2H	32296183
Intra	COL8A1	P27658	KPRP	Homo sapiens	Q5T749	Y2H Array	32296183
Intra	COL8A1	P27658	KPRP	Homo sapiens	Q5T749	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP1-3	Homo sapiens	Q8IUG1	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP1-3	Homo sapiens	Q8IUG1	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP12-3	Homo sapiens	P60328	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP12-3	Homo sapiens	P60328	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP12-3	Homo sapiens	P60328	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP6-2	Homo sapiens	Q3LI66	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	ACTMAP	Homo sapiens	Q5BKX5-3	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	ACTMAP	Homo sapiens	Q5BKX5-3	Validated Y2H	32296183
Intra	COL8A1	P27658	ACTMAP	Homo sapiens	Q5BKX5-3	Y2H Array	32296183
Intra	COL8A1	P27658	POF1B	Homo sapiens	Q8WVV4-1	Validated Y2H	32296183
Intra	COL8A1	P27658	POF1B	Homo sapiens	Q8WVV4-1	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	POF1B	Homo sapiens	Q8WVV4-1	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP5-7	Homo sapiens	Q6L8G8	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP5-7	Homo sapiens	Q6L8G8	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP5-7	Homo sapiens	Q6L8G8	Validated Y2H	32296183
Intra	COL8A1	P27658	WFDC5	Homo sapiens	Q8TCV5	Y2H Array	32296183
Intra	COL8A1	P27658	WFDC5	Homo sapiens	Q8TCV5	Validated Y2H	32296183
Intra	COL8A1	P27658	WFDC5	Homo sapiens	Q8TCV5	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP19-2	Homo sapiens	Q3LHN2	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP19-2	Homo sapiens	Q3LHN2	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP19-2	Homo sapiens	Q3LHN2	Y2H Array	32296183
Intra	COL8A1	P27658	FAM86C1P	Homo sapiens	Q9NVL1-2	Y2H Array	32296183
Intra	COL8A1	P27658	FAM86C1P	Homo sapiens	Q9NVL1-2	Validated Y2H	32296183
Intra	COL8A1	P27658	FAM86C1P	Homo sapiens	Q9NVL1-2	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	LIMS1	Homo sapiens	P48059-3	Validated Y2H	32296183
Intra	COL8A1	P27658	LIMS1	Homo sapiens	P48059-3	Y2H Array	32296183
Intra	COL8A1	P27658	LIMS1	Homo sapiens	P48059-3	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	SLC35A2	Homo sapiens	P78381-3	Validated Y2H	32296183
Intra	COL8A1	P27658	SLC35A2	Homo sapiens	P78381-3	Y2H Array	32296183
Intra	COL8A1	P27658	SLC35A2	Homo sapiens	P78381-3	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	POU4F2	Homo sapiens	Q12837	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	POU4F2	Homo sapiens	Q12837	Validated Y2H	32296183
Intra	COL8A1	P27658	POU4F2	Homo sapiens	Q12837	Y2H Array	32296183
Intra	COL8A1	P27658	RHBDD2	Homo sapiens	Q6NTF9-3	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	RHBDD2	Homo sapiens	Q6NTF9-3	Y2H Array	32296183
Intra	COL8A1	P27658	RHBDD2	Homo sapiens	Q6NTF9-3	Validated Y2H	32296183
Intra	COL8A1	P27658	TRIM35	Homo sapiens	Q9UPQ4-2	Validated Y2H	32296183
Intra	COL8A1	P27658	TRIM35	Homo sapiens	Q9UPQ4-2	Y2H Array	32296183
Intra	COL8A1	P27658	TRIM35	Homo sapiens	Q9UPQ4-2	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	MAJIN	Homo sapiens	Q3KP22-3	Y2H Array	32296183
Intra	COL8A1	P27658	MAJIN	Homo sapiens	Q3KP22-3	Validated Y2H	32296183
Intra	COL8A1	P27658	MAJIN	Homo sapiens	Q3KP22-3	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	DPEP2NB	Homo sapiens	A0A0U1RQF7	Y2H Array	32296183
Intra	COL8A1	P27658	DPEP2NB	Homo sapiens	A0A0U1RQF7	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	GSC2	Homo sapiens	O15499	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	GSC2	Homo sapiens	O15499	Y2H Array	32296183
Intra	COL8A1	P27658	VAC14	Homo sapiens	Q08AM6	Validated Y2H	32296183
Intra	COL8A1	P27658	VAC14	Homo sapiens	Q08AM6	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	VAC14	Homo sapiens	Q08AM6	Y2H Array	32296183
Intra	COL8A1	P27658	VAC14	Homo sapiens	Q08AM6	Y2H Array	29892012
Intra	COL8A1	P27658	VAC14	Homo sapiens	Q08AM6	Validated Y2H	25416956
Intra	COL8A1	P27658	NOTCH2NLC	Homo sapiens	P0DPK4	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	NOTCH2NLC	Homo sapiens	P0DPK4	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Array	32296183
Intra	COL8A1	P27658	ZNHIT1	Homo sapiens	O43257	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	ZNHIT1	Homo sapiens	O43257	Y2H Array	32296183
Intra	COL8A1	P27658	SPRY4	Homo sapiens	Q9C004	Validated Y2H	32296183
Intra	COL8A1	P27658	SPRY4	Homo sapiens	Q9C004	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	SPRY4	Homo sapiens	Q9C004	Y2H Array	32296183
Intra	COL8A1	P27658	GLRX3	Homo sapiens	O76003	Y2H Array	32296183
Intra	COL8A1	P27658	GLRX3	Homo sapiens	O76003	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
Intra	COL8A1	P27658	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	CCN3	Homo sapiens	P48745	Validated Y2H	32296183
Intra	COL8A1	P27658	CCN3	Homo sapiens	P48745	Y2H Array	32296183
Intra	COL8A1	P27658	CCN3	Homo sapiens	P48745	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP26-1	Homo sapiens	Q6PEX3	Validated Y2H	25416956
Intra	COL8A1	P27658	KRTAP5-9	Homo sapiens	P26371	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	KRTAP5-9	Homo sapiens	P26371	Y2H Array	32296183
Intra	COL8A1	P27658	ARMC5	Homo sapiens	Q96C12	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	ARMC5	Homo sapiens	Q96C12	Validated Y2H	32296183
Intra	COL8A1	P27658	ARMC5	Homo sapiens	Q96C12	Y2H Array	32296183
Intra	COL8A1	P27658	INCA1	Homo sapiens	Q0VD86	Validated Y2H	32296183
Intra	COL8A1	P27658	INCA1	Homo sapiens	Q0VD86	Y2H Array	31515488
Intra	COL8A1	P27658	INCA1	Homo sapiens	Q0VD86	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	INCA1	Homo sapiens	Q0VD86	Y2H Array	25416956
Intra	COL8A1	P27658	INCA1	Homo sapiens	Q0VD86	Y2H Array	32296183
Intra	COL8A1	P27658	CIDEB	Homo sapiens	Q9UHD4	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	CIDEB	Homo sapiens	Q9UHD4	Validated Y2H	32296183
Intra	COL8A1	P27658	CIDEB	Homo sapiens	Q9UHD4	Y2H Array	32296183
Intra	COL8A1	P27658	CFAP68	Homo sapiens	Q9H5F2	Y2H Array	32296183
Intra	COL8A1	P27658	CFAP68	Homo sapiens	Q9H5F2	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	CFAP68	Homo sapiens	Q9H5F2	Validated Y2H	32296183
Intra	COL8A1	P27658	FBXO34	Homo sapiens	Q9NWN3	Validated Y2H	32296183
Intra	COL8A1	P27658	FBXO34	Homo sapiens	Q9NWN3	Y2H Array	32296183
Intra	COL8A1	P27658	FBXO34	Homo sapiens	Q9NWN3	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	FRS3	Homo sapiens	O43559	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	FRS3	Homo sapiens	O43559	Y2H Array	32296183
Intra	COL8A1	P27658	C22orf39	Homo sapiens	Q6P5X5	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	C22orf39	Homo sapiens	Q6P5X5	Y2H Array	32296183
Intra	COL8A1	P27658	C22orf39	Homo sapiens	Q6P5X5	Validated Y2H	32296183
Intra	COL8A1	P27658	RBPMS	Homo sapiens	Q93062-3	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	RBPMS	Homo sapiens	Q93062-3	Validated Y2H	32296183
Intra	COL8A1	P27658	RBPMS	Homo sapiens	Q93062-3	Y2H Array	32296183
Intra	COL8A1	P27658	OTX1	Homo sapiens	P32242	Validated Y2H	32296183
Intra	COL8A1	P27658	HOXA1	Homo sapiens	P49639	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	HOXA1	Homo sapiens	P49639	Validated Y2H	32296183
Intra	COL8A1	P27658	HOXA1	Homo sapiens	P49639	Y2H Array	32296183
Intra	COL8A1	P27658	CEP55	Homo sapiens	Q53EZ4	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	CEP55	Homo sapiens	Q53EZ4	Validated Y2H	32296183
Intra	COL8A1	P27658	CEP55	Homo sapiens	Q53EZ4	Y2H Array	32296183
Intra	COL8A1	P27658	NADSYN1	Homo sapiens	Q6IA69	Validated Y2H	32296183
Intra	COL8A1	P27658	NADSYN1	Homo sapiens	Q6IA69	Y2H Array	32296183
Intra	COL8A1	P27658	NADSYN1	Homo sapiens	Q6IA69	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	PLSCR3	Homo sapiens	Q9NRY6	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	PLSCR3	Homo sapiens	Q9NRY6	Y2H Array	32296183
Intra	COL8A1	P27658	PLSCR3	Homo sapiens	Q9NRY6	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP3-2	Homo sapiens	Q9BYR7	Y2H Array	32296183
Intra	COL8A1	P27658	KRTAP3-2	Homo sapiens	Q9BYR7	Validated Y2H	32296183
Intra	COL8A1	P27658	KRTAP3-2	Homo sapiens	Q9BYR7	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	SPATA8	Homo sapiens	Q6RVD6	Validated Y2H	32296183
Intra	COL8A1	P27658	SPATA8	Homo sapiens	Q6RVD6	Y2H Array	32296183
Intra	COL8A1	P27658	SPATA8	Homo sapiens	Q6RVD6	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	NOTCH2NLA	Homo sapiens	Q7Z3S9	Y2H Prey Pooling	25416956
Intra	COL8A1	P27658	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183
Intra	COL8A1	P27658	UBQLN2	Homo sapiens	Q9UHD9	Y2H Array	32296183
Intra	COL8A1	P27658	UBQLN2	Homo sapiens	Q9UHD9	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	FBLN2	Homo sapiens	P98095	Validated Y2H	32296183
Intra	COL8A1	P27658	FBLN2	Homo sapiens	P98095	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	FBLN2	Homo sapiens	P98095	Y2H Array	32296183
Intra	COL8A1	P27658	BPIFA1	Homo sapiens	Q9NP55	Y2H Prey Pooling	32296183
Intra	COL8A1	P27658	BPIFA1	Homo sapiens	Q9NP55	Validated Y2H	32296183
Intra	COL8A1	P27658	BPIFA1	Homo sapiens	Q9NP55	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant COL8A1 Proteins

製品番号	製品名	アクセッション番号	純度
HY-P70018	Collagen alpha-1(VIII) chain/COL8A1 Protein, Human (HEK293, His)	P27658 (G28-M744)	≥ 95%, as determined by reducing SDS-PAGE.

関連疾患

Diseases	Alias
Corneal Endothelial Dystrophy	Congenital Hereditary Endothelial Dystrophy Of Cornea Chandler Syndrome CHED Chandler'S Syndrome Endothelial Corneal Dystrophy Ched2 Maumenee Corneal Dystrophy Corneal Dystrophy, Congenital Hereditary Endothelial Dystrophy Of Corneal Endothelium Corneal Endothelial Dystrophy 2 Corneal Endothelial Dystrophy 2, Autosomal Recessive, Formerly Ched2, Formerly Corneal Endothelial Dystrophy, Autosomal Recessive Endothelial Dystrophy Posterior Membrane Corneal Dystrophy Corneal Endothelial Dystrophy Type 2 Congenital Hereditary Endothelial Dystrophy Of The Cornea Congenital Hereditary Endothelial Dystrophy Type Ii Autosomal Recessive Ched Autosomal Recessive Congenital Hereditary Endothelial Dystrophy Chedii Congenital Hereditary Endothelial Dystrophy Type 2 Infantile Hereditary Endothelial Dystrophy Congenital Hereditary Endothelial Corneal Dystrophy Corneal Endothelial Dystrophy 2, Autosomal Recessive Iridocorneal Endothelial Syndrome Dystrophy, Corneal, Endothelial Corneal Endothelial Dystrophy 1, Autosomal Dominant
Corneal Dystrophy
Macular Degeneration, Age-Related, 1	Macular Degeneration Age-Related Macular Degeneration Macular Degeneration, Age-Related Age Related Macular Degeneration Age Related Macular Degeneration 1 ARMD1 Senile Macular Degeneration Maculopathy, Age-Related, 1 Macular Degeneration, Age-Related, Reduced Risk Of Age Related Maculopathy 1 Age Related Maculopathies Age Related Maculopathy Senile Macular Retinal Degeneration Macular Degeneration Of Retina Age-Related Maculopathy Amd Armd Age-Related Maculopathy, Susceptibility To Maculopathy Age-Related Macular Degeneration, Age-Related, 1, Susceptibility To Maculopathy, Age-Related Macular Degeneration, Age-Related, Type 1 Macular Degeneration, Age-Related, 2
Corneal Dystrophy, Posterior Polymorphous, 1	Posterior Polymorphous Corneal Dystrophy Ppcd Maumenee Corneal Dystrophy Posterior Polymorphous Corneal Dystrophy 1 PPCD1 Corneal Dystrophy, Hereditary Polymorphous Posterior Corneal Endothelial Dystrophy 1, Autosomal Dominant Schlichting Dystrophy Ched1 Corneal Endothelial Dystrophy 1, Autosomal Dominant, Formerly Ched1, Formerly Hereditary Polymorphus Posterior Corneal Dystrophy Posterior Polymorphous Dystrophy Hereditary Polymorphous Posterior Corneal Dystrophy Dystrophy, Corneal, Posterior Polymorphous Dystrophy, Corneal, Posterior Polymorphous, Type 1 Polymorphous Corneal Dystrophy Corneal Endothelial Dystrophy 2
Keratoconus	Kc Conical Cornea Noninflammatory Corneal Thining Bulging Cornea Cornea Conical Acquired Conus Of Cornea
Sorsby Fundus Dystrophy	SFD Fundus Dystrophy, Pseudoinflammatory, Of Sorsby Sorsby'S Fundus Dystrophy Macular Dystrophy, Hemorrhagic Hemorrhagic Macular Dystrophy Pseudoinflammatory Fundus Dystrophy Of Sorsby Sorsby'S Pseudoinflammatory Macular Dystrophy Sorsby Pseudoinflammatory Fundus Dystrophy Dystrophy, Fundus, Sorsby
Degenerative Myopia	Pathological Myopia Myopia, Degenerative Degenerative Progressive High Myopia Progressive High Myopia Progressive High Myopia
Fuchs' Endothelial Dystrophy	Fuchs Endothelial Corneal Dystrophy Fuchs Endothelial Dystrophy Fuchs Dystrophy Fced Fuchs' Corneal Dystrophy Fuchs' Endothelial Corneal Dystrophy Fuchs Atrophy Fuchs Corneal Dystrophy Endoepithelial Corneal Dystrophy Fecd Late Hereditary Endothelial Dystrophy Corneal Dystrophy, Fuchs Endothelial Dystrophy, Corneal, Fuchs Endothelial Corneal Dystrophy, Fuchs' Endothelial, 1
Adamantinous Craniopharyngioma	Adamantinous Rathke'S Pouch Tumor Craniopharyngioma, Adamantinomatous Adamantinomatous Craniopharyngioma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS02998	COL8A1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS18858	Col8a1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS25350	Col8a1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Felis catus	COL8A1	VGNC	VGNC:61070
Bos taurus	COL8A1	VGNC	VGNC:27574
Rattus norvegicus	COL8A1	RGD	RGD:1309361
Macaca mulatta	COL8A1	VGNC	VGNC:71304
Canis familiaris	COL8A1	VGNC	VGNC:39484
Mus musculus	COL8A1	MGD	MGI:88463
Others	COL8A1	NCBI