Nsf - N-ethylmaleimide sensitive fusion protein Gene

Also Known as SKD2

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 18195

Summary

Enables ATP hydrolysis activity; protein kinase binding activity; and syntaxin-1 binding activity. Acts upstream of or within potassium ion transport. Located in myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy. Orthologous to human NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase). [provided by Alliance of Genome Resources, Apr 2022]

Nsf Products (1)

mRNA Protein Name
NM_008740.4 NP_032766.2 vesicle-fusing ATPase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables ATP hydrolysis activity IMP
IMP: Inferred from mutant phenotype
12832401 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15322554 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
21307259 MGI
enables syntaxin binding IDA
IDA: Inferred from direct assay
14755058 MGI
enables syntaxin-1 binding IDA
IDA: Inferred from direct assay
21307259 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within potassium ion transport IDA
IDA: Inferred from direct assay
8082782 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vesicle-fusing ATPase

  • N-ethylmaleimide sensitive factor

  • NEM-sensitive fusion protein

  • suppressor of K(+) transport growth defect 2

  • vesicular-fusion protein NSF

Nsf Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
Nsf P46460 Lrrk2 Mus musculus Q5S006
Anti Bait CoIP
21307259
Intra
Nsf P46460 Dlg4 Mus musculus Q62108
Anti Bait CoIP
19455133
Intra
Nsf P46460 Musk Mus musculus Q61006-3
ELISA
18272689
Intra
Nsf P46460 Musk Mus musculus Q61006-3
Anti Tag CoIP
18272689
Intra
Nsf P46460 Musk Mus musculus Q61006-3
Y2H
18272689
Intra
Nsf P46460 Ptpn9 Mus musculus O35239
Pull Down
15322554
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS09591 NSF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P4114 TAT-NSF700scr 95.17% Unkown
HY-P1399A Pep2m, myristoylated TFA Inhibitor 99.77% Unkown
HY-P1057 Pep4c Control / Unkown
HY-P1058 Pep2m Inhibitor / Unkown
HY-P1399 Pep2m, myristoylated Inhibitor / Unkown
HY-P4110 TAT-NSF222 Fusion Peptide Inhibitor / Unkown
HY-118460 ACJI-99C Inhibitor / Unkown
HY-149590 IPA Chemical / Unkown
HY-N12768 Rhodojaponin VI Inhibitor / Unkown
HY-RS16783 Nsf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23223 Nsf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Nsf NCBI NCBI:4905