PAQR8 - progestin and adipoQ receptor family member 8 Gene

Also Known as MPRB; LMPB1; C6orf33

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 85315

About PAQR8

Cytogenetic location: 6p12.2 Genomic coordinates (GRCh38): 6:52,362,151-52,407,777 (from NCBI)

This gene has 3 transcripts (splice variants), 225 orthologues and 10 paralogues. Broad expression in brain (RPKM 26.8), colon (RPKM 23.1) and 21 other tissues.

Summary

Predicted to enable steroid binding activity and steroid hormone receptor activity. Predicted to be involved in response to steroid hormone. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

PAQR8 Products (1)

mRNA Protein Name
NM_133367.5 NP_588608.1 membrane progestin receptor beta

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PAQR8 Protein Structure

HlyIII

HlyIII: Haemolysin-III related (70 - 296)

  • 0
  • 100
  • 200
  • 300
  • 354 a.a.
Protein Preferred Names Protein Names

membrane progestin receptor beta

  • lysosomal membrane protein in brain-1

PAQR8 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
PAQR8 Q8TEZ7 LEPROTL1 Homo sapiens O95214
Y2H Prey Pooling
32296183
Intra
PAQR8 Q8TEZ7 LEPROTL1 Homo sapiens O95214
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Myositis Fibrosa

  • Interstitial Myositis
Epilepsy, Myoclonic Juvenile

  • Juvenile Myoclonic Epilepsy

  • Janz Syndrome

  • Jme

  • Myoclonic Epilepsy, Juvenile, Susceptibility To, 1

  • EJM

  • Myoclonic Epilepsy, Juvenile

  • Petit Mal, Impulsive

  • Myoclonic Epilepsy, Juvenile 1

  • Myoclonic Epilepsy, Juvenile, 1

  • Adolescent Myoclonic Epilepsy

  • Juvenile Myoclonus Epilepsy

  • Juvenile Myoclonic Epilepsy 1

  • EJM1

  • Petit Mal Impulsive

  • Susceptibility To Juvenile Myoclonic Epilepsy 1

  • Myoclonic Epilepsy Juvenile

  • Epilepsy, Myoclonic, Juvenile

  • Myoclonic Epilepsy Of Janz

  • Jme - [Juvenile Myoclonic Epilepsy]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS10035 PAQR8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus PAQR8 VGNC VGNC:32580
Macaca mulatta PAQR8 VGNC VGNC:75610
Canis familiaris PAQR8 VGNC VGNC:57227
Felis catus PAQR8 VGNC VGNC:102480
Mus musculus PAQR8 MGD MGI:1921479
Rattus norvegicus PAQR8 RGD RGD:1311710
Others PAQR8 NCBI