PAQR8 - progestin and adipoQ receptor family member 8 Gene

Homo sapiens

Also known as MPRB; LMPB1; C6orf33

Gene ID: 85315 | Gene type: protein coding

About PAQR8

Cytogenetic location: 6p12.2 Genomic coordinates (GRCh38): 6:52,362,151-52,407,777 (from NCBI)

This gene has 3 transcripts (splice variants), 225 orthologues and 10 paralogues. Broad expression in brain (RPKM 26.8), colon (RPKM 23.1) and 21 other tissues.

Summary

Predicted to enable steroid binding activity and steroid hormone receptor activity. Predicted to be involved in response to steroid hormone. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

PAQR8 Products(1)

mRNA	Protein	Name
NM_133367.5	NP_588608.1	membrane progestin receptor beta

PAQR8 Protein Structure

HlyIII

0
100
200
300
354 a.a.

Protein Preferred Names

Protein Names

membrane progestin receptor beta

lysosomal membrane protein in brain-1

Related Diseases

Diseases

Alias

Myositis Fibrosa

Interstitial Myositis

Epilepsy, Myoclonic Juvenile

Juvenile Myoclonic Epilepsy	Janz Syndrome
Jme	Myoclonic Epilepsy, Juvenile, Susceptibility To, 1
EJM	Myoclonic Epilepsy, Juvenile
Petit Mal, Impulsive	Myoclonic Epilepsy, Juvenile 1
Myoclonic Epilepsy, Juvenile, 1	Adolescent Myoclonic Epilepsy
Juvenile Myoclonus Epilepsy	Juvenile Myoclonic Epilepsy 1
EJM1	Petit Mal Impulsive
Susceptibility To Juvenile Myoclonic Epilepsy 1	Myoclonic Epilepsy Juvenile
Epilepsy, Myoclonic, Juvenile	Myoclonic Epilepsy Of Janz
Jme - [Juvenile Myoclonic Epilepsy]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10035	PAQR8 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PAQR8	VGNC	VGNC:32580
Macaca mulatta	PAQR8	VGNC	VGNC:75610
Canis familiaris	PAQR8	VGNC	VGNC:57227
Felis catus	PAQR8	VGNC	VGNC:102480
Mus musculus	PAQR8	MGD	MGI:1921479
Rattus norvegicus	PAQR8	RGD	RGD:1311710

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