Glucose-PEG2000-N3
Glucose-PEG2000-N3 (Glucose-PEG2000-Azide) is a conjugate composed of glucose, PEG chains, and an azide group (-N3). Glucose-PEG2000-N3 combines the targeted recognition ability of glucose with the azide group that can undergo click chemistry, making it suitable for applications such as constructing targeted drug delivery systems and nanoparticle modification.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
The structure of Glucose-PEG-N3 comprises three key components that work synergistically:
Glucose: Specifically recognizes and binds to glucose transporters (such as GLUT1) highly expressed on the surface of various cells (especially tumor cells), achieving receptor-mediated active targeted delivery.
PEG chain: Acts as a hydrophilic spacer, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, and prolonging the carrier's circulation time in vivo.
Azide group: Can undergo copper-catalyzed azido-azide cycloaddition (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven azido-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
OC1O[C@H]([C@@H]([C@H]([C@@H]1NC(OCCOCCN=[N+]=[N-])=O)O)O)CO.[n]
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別名
Glucose-PEG2000-Azide
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)