GSK9027
Based on 1 Customer Validation
GSK9027, as a non-steroidal glucocorticoid receptor (GR) agonist, behaves as a partial agonist on the 2×glucocorticoid response element (GRE) reporter system, and achieves intrinsic activities relative to dexamethasone.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.59%
- CAS 番号: 1229096-88-1
- 分子式: C27H19F4N3O2S
- 分子量:525.52
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-14234
Glucocorticoid receptor agonist -
HY-13580
Budesonide -
HY-N0583
Hydrocortisone -
HY-17463
Prednisolone -
HY-B0625
Ciclesonide -
HY-B0248
Desonide -
HY-13570
Betamethasone -
HY-B0154
Fluticasone propionate -
HY-B0415
Fluocinolone (Acetonide) -
HY-14648
Dexamethasone -
HY-131974
Glucocorticoid receptor agonist-1 -
HY-111453
Velsecorat
生物活性
製品説明
IC50 & Target
GR[2]
体外実験
GSK9027 demonstrates reduced 2×GRE reporter activation and is partial agonists[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1229096-88-1
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性状 Solid
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分子量 525.52
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分子式 C27H19F4N3O2S
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Color White to off-white
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SMILES
O=S(CC1=CC=CC=C1)(NC2=CC=C(C3=CC4=C(N(C5=CC=C(F)C=C5)N=C4)C=C3)C(C(F)(F)F)=C2)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 250 mg/mL (475.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9029 mL | 9.5144 mL | 19.0288 mL | 47.5719 mL |
| 5 mM | 0.3806 mL | 1.9029 mL | 3.8058 mL | 9.5144 mL | |
| 10 mM | 0.1903 mL | 0.9514 mL | 1.9029 mL | 4.7572 mL | |
| 15 mM | 0.1269 mL | 0.6343 mL | 1.2686 mL | 3.1715 mL | |
| 20 mM | 0.0951 mL | 0.4757 mL | 0.9514 mL | 2.3786 mL | |
| 25 mM | 0.0761 mL | 0.3806 mL | 0.7612 mL | 1.9029 mL | |
| 30 mM | 0.0634 mL | 0.3171 mL | 0.6343 mL | 1.5857 mL | |
| 40 mM | 0.0476 mL | 0.2379 mL | 0.4757 mL | 1.1893 mL | |
| 50 mM | 0.0381 mL | 0.1903 mL | 0.3806 mL | 0.9514 mL | |
| 60 mM | 0.0317 mL | 0.1586 mL | 0.3171 mL | 0.7929 mL | |
| 80 mM | 0.0238 mL | 0.1189 mL | 0.2379 mL | 0.5946 mL | |
| 100 mM | 0.0190 mL | 0.0951 mL | 0.1903 mL | 0.4757 mL |
GSK9027 関連分類
HY-103548 関連分類
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