Gymconopin C
Gymconopin C shows an antiallergic effect on ear passive cutaneous anaphylaxis reactions in mice.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 844493-85-2
- 分子式: C30H26O6
- 分子量:482.52
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
12 μM
Compound: 24
|
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess assay
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess assay
|
[PMID: 31415170] |
| Neutrophil | IC50 |
0.5 μM
Compound: 25
|
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
|
[PMID: 27525452] |
| Neutrophil | IC50 |
1.5 μM
Compound: 25
|
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
|
[PMID: 27525452] |
化学情報
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CAS 番号 844493-85-2
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分子量 482.52
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分子式 C30H26O6
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SMILES
OC1=CC=C2C(CCC3=C(C4=C(O)C=C(CCC5=CC(O)=CC(OC)=C65)C6=C4)C(O)=CC(OC)=C23)=C1
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)