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製品番号: HY-118205

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SCH-538415

SCH-538415 is a novel acyl carrier protein synthase inhibitor isolated from an unknown bacterial microorganism. The structural elucidation of compound 1 was completed by analyzing spectral data including UV, MS and 2D-NMR spectra. Compound 1 showed inhibitory activity in the acyl carrier protein synthase (AcpS) test with an IC50 value of 4.19 μM and exhibited antibacterial activity against Staphylococcus aureus in the agar diffusion test.

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CAS 番号: 637772-75-9
分子式: C₁₆H₁₄N₂O₄
分子量:298.29

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

SCH-538415 構造式

CAS 番号: 637772-75-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
BXPC-3	GI₅₀	0.54 μg/mL Compound: 1, SCH-538415	Growth inhibition of human BXPC3 cells Growth inhibition of human BXPC3 cells	[PMID: 16724845]
DU-145	GI₅₀	1 μg/mL Compound: 1, SCH-538415	Growth inhibition of human DU145 cells Growth inhibition of human DU145 cells	[PMID: 16724845]
KM-20L2	GI₅₀	0.32 μg/mL Compound: 1, SCH-538415	Growth inhibition of human KM20L2 cells Growth inhibition of human KM20L2 cells	[PMID: 16724845]
MCF7	GI₅₀	0.49 μg/mL Compound: 1, SCH-538415	Growth inhibition of human MCF7 cells Growth inhibition of human MCF7 cells	[PMID: 16724845]
NCI-H460	GI₅₀	1.2 μg/mL Compound: 1, SCH-538415	Growth inhibition of human NCI-H460 cells Growth inhibition of human NCI-H460 cells	[PMID: 16724845]
P388	GI₅₀	1.4 μg/mL Compound: 1, SCH-538415	Growth inhibition of mouse P388 cells Growth inhibition of mouse P388 cells	[PMID: 16724845]
SF-268	GI₅₀	1.3 μg/mL Compound: 1, SCH-538415	Growth inhibition of human SF268 cells Growth inhibition of human SF268 cells	[PMID: 16724845]

化学情報

CAS 番号 637772-75-9
分子量 298.29
分子式 C₁₆H₁₄N₂O₄
SMILES

O=C1N(C2=C(C(C)=C1)C(C(C(C)=C3)=C(C2=O)N(C)C3=O)=O)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (267 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Structure elucidation of Sch 538415, a novel acyl carrier protein synthase inhibitor from a microorganism

Calculators

モル濃度計算機

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分子量分子量

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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