Kir4.1-IN-1
Based on 1 Customer Validation
Kir4.1-IN-1 (Compound 37) is a potent, selective, blood-brain barrier permeable Kir4.1 inhibitor with an IC50 of 0.19 μM. Kir4.1-IN-1 exhibits rapid-onset antidepressant effects.
For research use only. We do not sell to patients.
- Purity: 99.07%
- Formula: C24H27N5S
- Molecular Weight:417.57
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Kir4.1 0.19 μM (IC50) |
Chemical Information
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Appearance Solid
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Molecular Weight 417.57
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Formula C24H27N5S
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Color White to off-white
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SMILES
C1(NCCCN2CCCCC2)=NC=CC(NC3=CC4=C(SC5=C4C=CC=C5)C=C3)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (119.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3948 mL | 11.9740 mL | 23.9481 mL | 59.8702 mL |
| 5 mM | 0.4790 mL | 2.3948 mL | 4.7896 mL | 11.9740 mL | |
| 10 mM | 0.2395 mL | 1.1974 mL | 2.3948 mL | 5.9870 mL | |
| 15 mM | 0.1597 mL | 0.7983 mL | 1.5965 mL | 3.9913 mL | |
| 20 mM | 0.1197 mL | 0.5987 mL | 1.1974 mL | 2.9935 mL | |
| 25 mM | 0.0958 mL | 0.4790 mL | 0.9579 mL | 2.3948 mL | |
| 30 mM | 0.0798 mL | 0.3991 mL | 0.7983 mL | 1.9957 mL | |
| 40 mM | 0.0599 mL | 0.2994 mL | 0.5987 mL | 1.4968 mL | |
| 50 mM | 0.0479 mL | 0.2395 mL | 0.4790 mL | 1.1974 mL | |
| 60 mM | 0.0399 mL | 0.1996 mL | 0.3991 mL | 0.9978 mL | |
| 80 mM | 0.0299 mL | 0.1497 mL | 0.2994 mL | 0.7484 mL | |
| 100 mM | 0.0239 mL | 0.1197 mL | 0.2395 mL | 0.5987 mL |