1476735-95-1
Chemical Structure
IETDC
- CAS No.: 1476735-95-1
- Formula:C32H47N5O13S
- Molecular Weight:741.81
InChIKey: ZPRBDOUPFFCFMW-YPGSYSQBSA-N
SMILES: O=C([C@@H](NC(OCC1=CC=CC=C1)=O)[C@H](CC)C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(O)=O)CS)=O)CC(OC)=O)=O)[C@@H](C)O)=O)CCC(OC)=O
Biological Activity: IETDC is a caspase 8-responsive fluorescent probe. IETDC is cleaved by activated caspase 8 to release D-cysteine, which then reacts with 6-hydroxy-2-cyanobenzothiazole (HCBT) to form firefly luciferin in situ. IETDC must be used in conjunction with PCL-2 (HY-D3168) to detect the co-existence of hydrogen peroxide and caspase 8. IETDC is applicable to studies related to acute inflammation[1].
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IETDC | IETDC is a caspase 8-responsive fluorescent probe. IETDC is cleaved by activated caspase 8 to release D-cysteine, which then reacts with 6-hydroxy-2-cyanobenzothiazole (HCBT) to form firefly luciferin in situ. IETDC must be used in conjunction with PCL-2 (HY-D3168) to detect the co-existence of hydrogen peroxide and caspase 8. IETDC is applicable to studies related to acute inflammation. | |||||||||||||||||||||
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