3-Arm PEG10000-Azide
3-Arm PEG10000-Azide (3-Arm PEG10000-N3) is a three-armed PEG derivative. The core structure of 3-Arm PEG10000-Azide consists of three PEG chains, each terminal of which is modified with an azide (-N3) group. The azide group in 3-Arm PEG10000-Azide can undergo click chemistry reactions and is used for applications such as constructing targeted drug delivery systems and nanoparticle modification.
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- 분자량:10000 (Average)
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
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Help & FAQs
Biological Activity
The structure of PEG-Azide contains two key parts that work synergistically:
Azide group: can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
PEG chain: As a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 10000 (Average)
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SMILES
CCC(COCCOCCN=[N+]=[N-])(COCCOCCN=[N+]=[N-])COCCOCCN=[N+]=[N-].[n].[n].[n]
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Synonyms
3-Arm PEG10000-N3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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