AT-1015
AT-1015 is a selective and orally active 5-HT2A serotonin receptor antagonist. AT-1015 exhibits antithrombotic effect. AT-1015 prolongs the time needed to occlusion of the artery with thrombus. AT-1015 impairs platelet aggregation and vasoconstriction.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 190508-48-6
- 화학식: C29H36ClN3O3
- 분자량:510.07
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 190508-48-6
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분자량 510.07
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화학식 C29H36ClN3O3
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SMILES
O=C(C1CCN(C=O)CC1)NCCN2CC/C(CC2)=C3C4=CC=CC=C4C=CC5=CC=CC=C/35.O.Cl
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Hiatt, W. R., et al., (2004). Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacy. Vascular medicine (London, England), 9(1), 18-25. [Content Brief]
[2]. Kihara, H., et al., (2001). Antithrombotic activity of AT-1015, a potent 5-HT(2A) receptor antagonist, in rat arterial thrombosis model and its effect on bleeding time. European journal of pharmacology, 433(2-3), 157-162. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)