32746-94-4
32746-94-4
Chemical Structure
Ampicilloic acid
Synonym(s): Ampicillin impurity D
- CAS No.: 32746-94-4
- Formula:C16H21N3O5S
- Molecular Weight:367.42
IUPAC Name: (2R,4S)-2-((R)-((R)-2-amino-2-phenylacetamido)(carboxy)methyl)-5,5-dimethylthiazolidine-4-carboxylic acid
InChIKey: KDAWOPKDXRJNHV-MPPDQPJWSA-N
SMILES: [C@@H](NC([C@H](N)C1=CC=CC=C1)=O)(C(O)=O)[C@@]2(N[C@@H](C(O)=O)C(C)(C)S2)[H]
Biological Activity: Ampicilloic acid (Ampicillin impurity D) is a hydrolytic metabolite of the penicillin antibiotic Ampicillin (HY-B0522), produced by Alcanivorax sp. via β-lactamase-mediated β-lactam ring opening reaction[1][2].
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Ampicilloic acid | Ampicilloic acid (Ampicillin impurity D) is a hydrolytic metabolite of the penicillin antibiotic Ampicillin (HY-B0522), produced by Alcanivorax sp. via β-lactamase-mediated β-lactam ring opening reaction. | |||||||||||||||||||||
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References
- [1]. Waghmare V, et al. Biotransformation of ampicillin antibiotic molecule using soil derived bacterium belonging to Alcanivorax sp. Asian Journal of Microbiology, Biotechnology & Environmental Sciences. 2020;22(4):594-598.
- [2]. Fernandez-Torres R, et al. Application of enzymatic probe sonication extraction for the determination of selected veterinary antibiotics and their main metabolites in fish and mussel samples. Analytica chimica acta. 2010 Aug 24;675(2):156-64. [Content Brief]
