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Cat. No.: HY-177534

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MGL-IN-2

MGL-IN-2 (Compound 1) is a MGL inhibitor with IC₅₀ values of 0.006 μM and 0.0121 μM for mutant MGL and wild-type MGL, respectively. MGL-IN-2 can be used in the research of metabolic diseases.

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CAS No.: 1252773-92-4
화학식: C₂₁H₁₈ClF₃N₄O₂S₂
분자량:514.97

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

MGL-IN-2 Chemical Structure

CAS No.: 1252773-92-4

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
Protocol (1)
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

IC₅₀: 0.006 μM and 0.0121 μM for mutant MGL and wild-type MGL, respectively^[1]

Chemical Information

CAS No. 1252773-92-4
분자량 514.97
화학식 C₂₁H₁₈ClF₃N₄O₂S₂
SMILES

O=C(C1=CSC=N1)N2CCN(C3CN(C(C4=C(Cl)C5=CC=C(C(F)(F)F)C=C5S4)=O)C3)CC2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocol

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Margery CONNELLY, et al. Monoacylglycerol lipase inhibitors for the treatment of metabolic diseases and related disorders. WO2013049293A1. WIPO (PCT). 2012-09-27.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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