ST4070
ST4070 is a potent, orally active, and selective reversible fatty acid amide hydrolase (FAAH) inhibitor. ST4070 increases endocannabinoid (eCB) brain levels and counteracts neuropathic pain in animal models. ST4070 enhances the endogenous eCB tone in specific brain regions engaged in emotional control, and induces remarkable anxiolytic-like behaviours in rodents. ST4070 can be used for neuropathic pain and anxiety disorders research.
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- CAS No.: 1186236-75-8
- 화학식: C20H21NO2
- 분자량:307.39
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1186236-75-8
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분자량 307.39
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화학식 C20H21NO2
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SMILES
O=C(N1CCCCC1)OC(C2=CC=C(C3=CC=CC=C3)C=C2)=C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Costanzo MJ, et al. Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2114-21. [Content Brief]
[2]. Marco EM, et al. Potential Therapeutic Value of a Novel FAAH Inhibitor for the Treatment of Anxiety. PLoS One. 2015 Sep 11;10(9):e0137034. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)