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Cat. No.: HY-176126

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STING agonist-42

STING agonist-42 (compound 8a) is a potent STING agonist. STING agonist-42 activates STING in THP1 and RAW 264.7 cells with EC₅₀s of 0.06 and 14.15 μM, respectively.

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CAS No.: 2942231-48-1
화학식: C₁₇H₈F₂LiN₅O₃
분자량:375.21

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

STING agonist-42 Chemical Structure

CAS No.: 2942231-48-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

STING agonist-42 (compound 8a) is a potent STING agonist. STING agonist-42 activates STING in THP1 and RAW 264.7 cells with EC₅₀s of 0.06 and 14.15 μM, respectively^[1].

Chemical Information

CAS No. 2942231-48-1
분자량 375.21
화학식 C₁₇H₈F₂LiN₅O₃
SMILES

FC1=CC(C(O[Li])=O)=C(NC(C2=NN=C(C=C2)N3C=NC(F)=C3)=O)C=C1C#C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hou H, et al. Discovery of 3-(Fluoro-imidazolyl)pyridazine Derivatives as Potent STING Agonists with Antitumor Activity. J Med Chem. 2025 May 9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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