KRAS G12C inhibitor 43
KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively.
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- CAS No.: 2648808-69-7
- Formule: C33H35N7O3
- Masse moléculaire:577.68
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
KRas G12C |
Chemical Information
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CAS No. 2648808-69-7
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Masse moléculaire 577.68
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Formule C33H35N7O3
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SMILES
C=CC(N1CCN(C[C@@H]1CC#N)C2=C3C=CC(C4=C5C=CC=CC5=CC(OC)=C4)=NC3=NC(OC[C@@H]6CCCN6C)=N2)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)