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  3. KRAS G12C inhibitor 43

KRAS G12C inhibitor 43 

Cat. No.: HY-142945
Handling Instructions

KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively.

For research use only. We do not sell to patients.

KRAS G12C inhibitor 43 Chemical Structure

KRAS G12C inhibitor 43 Chemical Structure

CAS No. : 2648808-69-7

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Description

KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively[1].

IC50 & Target[1]

KRas G12C

 

Molecular Weight

577.68

Formula

C33H35N7O3

CAS No.
SMILES

C=CC(N1CCN(C[[email protected]@H]1CC#N)C2=C3C=CC(C4=C5C=CC=CC5=CC(OC)=C4)=NC3=NC(OC[[email protected]@H]6CCCN6C)=N2)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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KRAS G12C inhibitor 43
Cat. No.:
HY-142945
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