KRAS G12C inhibitor 43
KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively.
For research use only. We do not sell to patients.
- CAS No.: 2648808-69-7
- Formula: C33H35N7O3
- Molecular Weight:577.68
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
KRas G12C |
Chemical Information
-
CAS No. 2648808-69-7
-
Molecular Weight 577.68
-
Formula C33H35N7O3
-
SMILES
C=CC(N1CCN(C[C@@H]1CC#N)C2=C3C=CC(C4=C5C=CC=CC5=CC(OC)=C4)=NC3=NC(OC[C@@H]6CCCN6C)=N2)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)