KRAS G12C inhibitor 44
KRAS G12C inhibitor 44 (compound 54) is a potent and orally active KRAS G12C inhibitor. KRAS G12C inhibitor 44 shows anti-proliferation activities with IC50s of 0.016, 0.028 µM in MIA PaCA-2, H358 cells, respectively. KRAS G12C inhibitor 44 shows antitumor effects in vivo.
For research use only. We do not sell to patients.
- CAS No.: 2927439-07-2
- Formula: C31H36ClFN6O2
- Molecular Weight:579.11
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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KRas G12C |
Chemical Information
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CAS No. 2927439-07-2
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Molecular Weight 579.11
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Formula C31H36ClFN6O2
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SMILES
ClC1=C2C([C@]3(CC2)CC4=NC(OC[C@H]5N(CCC5)C)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C4CC3)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)