1. Others Metabolic Enzyme/Protease Membrane Transporter/Ion Channel
  2. Potassium Channel Endogenous Metabolite Isotope-Labeled Compounds
  3. L-Palmitoylcarnitine-d9

L-Palmitoylcarnitine-d9 is deuterium labeled L-Palmitoylcarnitine. L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2.

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L-Palmitoylcarnitine-d<sub>9</sub>

L-Palmitoylcarnitine-d9 Chemical Structure

CAS No. : 2847775-90-8

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Other Forms of L-Palmitoylcarnitine-d9:

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Description

L-Palmitoylcarnitine-d9 is deuterium labeled L-Palmitoylcarnitine. L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1][1][2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Molecular Weight

408.66

Formula

C23H36D9NO4

CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCCCC(O[C@H](CC([O-])=O)C[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 25 mg/mL (61.18 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4470 mL 12.2351 mL 24.4702 mL
5 mM 0.4894 mL 2.4470 mL 4.8940 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 2.4470 mL 12.2351 mL 24.4702 mL 61.1755 mL
5 mM 0.4894 mL 2.4470 mL 4.8940 mL 12.2351 mL
10 mM 0.2447 mL 1.2235 mL 2.4470 mL 6.1176 mL
15 mM 0.1631 mL 0.8157 mL 1.6313 mL 4.0784 mL
20 mM 0.1224 mL 0.6118 mL 1.2235 mL 3.0588 mL
25 mM 0.0979 mL 0.4894 mL 0.9788 mL 2.4470 mL
30 mM 0.0816 mL 0.4078 mL 0.8157 mL 2.0392 mL
40 mM 0.0612 mL 0.3059 mL 0.6118 mL 1.5294 mL
50 mM 0.0489 mL 0.2447 mL 0.4894 mL 1.2235 mL
60 mM 0.0408 mL 0.2039 mL 0.4078 mL 1.0196 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
L-Palmitoylcarnitine-d9
Cat. No.:
HY-113147S1
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