L-Palmitoylcarnitine-d9
Based on 1 Customer Validation
L-Palmitoylcarnitine-d9 is deuterium labeled L-Palmitoylcarnitine. L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 2847775-90-8
- Formula: C23H36D9NO4
- Molecular Weight:408.66
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2847775-90-8
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Unlabeled Cas 2364-67-2
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Appearance Solid
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Molecular Weight 408.66
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Formula C23H36D9NO4
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Color White to off-white
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SMILES
CCCCCCCCCCCCCCCC(O[C@H](CC([O-])=O)C[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
Ethanol : 25 mg/mL (61.18 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Haruna T, et al. Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates K(ATP) channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000;441(2-3):200-207. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 2.4470 mL | 12.2351 mL | 24.4702 mL | 61.1755 mL |
| 5 mM | 0.4894 mL | 2.4470 mL | 4.8940 mL | 12.2351 mL | |
| 10 mM | 0.2447 mL | 1.2235 mL | 2.4470 mL | 6.1176 mL | |
| 15 mM | 0.1631 mL | 0.8157 mL | 1.6313 mL | 4.0784 mL | |
| 20 mM | 0.1224 mL | 0.6118 mL | 1.2235 mL | 3.0588 mL | |
| 25 mM | 0.0979 mL | 0.4894 mL | 0.9788 mL | 2.4470 mL | |
| 30 mM | 0.0816 mL | 0.4078 mL | 0.8157 mL | 2.0392 mL | |
| 40 mM | 0.0612 mL | 0.3059 mL | 0.6118 mL | 1.5294 mL | |
| 50 mM | 0.0489 mL | 0.2447 mL | 0.4894 mL | 1.2235 mL | |
| 60 mM | 0.0408 mL | 0.2039 mL | 0.4078 mL | 1.0196 mL |