Hydroxy/hydroperoxyeicosatetraenoic Acids

15(R)-HETE is an isomer of 15-HETE. 15-HETE is a lipid mediator derived from arachidonic acid and can be used for the study of asthma.

8(S)-HPETE, short for 8(S)-hydroperoxy-5Z,9E,11Z,14Z-eicosatetraenoic acid, is a major oxygenation product generated when arachidonic acid acts as a substrate for the lipoxygenase purified from ripe tomato fruits.

5-oxo-ETE is a potent chemoattractant for eosinophils. 5-oxo-ETE inhibits selenium-induced apoptosis in prostate cancer cells. 5-oxo-ETE can be used in research into asthma, allergic diseases, cancer and cardiovascular disease.

9(S)-HPETE is an intermediate in the biosynthesis of dictyopterene A in the freshwater diatom Gomphonema parvulum.

19(S)-HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. 19(S)-HETE is a full orthosteric agonist of the prostacyclin (IP) receptor with an EC₅₀ value of 567 nM. 19(S)-HETE inhibits platelet activation and relaxation of vessels.

5(S),12(S)-Leukotriene B4 (5(S),12(S)-LTB4; 5(S),12(S)-DiHETE) is a stereochemical isomer of LTB4 (HY-107608).

11-S-Hydroxyeicosatetraenoic acid (11(S)-Hydroxy-5(Z),8(Z),12(E),14(Z)-eicosatetraenoic acid) is an ester product.