MC-Phe-Lys(MMT)-PABOH
MC-Phe-Lys(MMT)-PABOH is a linker. MC-Phe-Lys(MMT)-PABOH can be used to synthesize the immunoconjugate BR96-Phe-Lys-PABC-DOX. MC-Phe-Lys(MMT)-PABOH can be used in the research of colorectal cancer and ovarian cancer.
For research use only. We do not sell to patients.
- CAS No.: 159857-65-5
- Formula: C52H57N5O7
- Molecular Weight:864.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 159857-65-5
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Molecular Weight 864.04
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Formula C52H57N5O7
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SMILES
O=C(C=CC1=O)N1CCCCCC(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(NC3=CC=C(C=C3)CO)=O)CCCCNC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=C(C=C6)OC)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Dubowchik GM, et al. Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: model studies of enzymatic drug release and antigen-specific in vitro anticancer activity. Bioconjug Chem. 2002 Jul-Aug;13(4):855-69. [Content Brief]
[2]. Yao H, et al. Methods to Design and Synthesize Antibody-Drug Conjugates (ADCs). Int J Mol Sci. 2016 Feb 2;17(2):194. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)