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  4. N-Methyl-N-tetradecanoylglycine

N-Methyl-N-tetradecanoylglycine is a rectal absorption promoter. N-Methyl-N-tetradecanoylglycine enhances rectal absorption of antibiotics.

For research use only. We do not sell to patients.

N-Methyl-N-tetradecanoylglycine

N-Methyl-N-tetradecanoylglycine Chemical Structure

CAS No. : 52558-73-3

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N-Methyl-N-tetradecanoylglycine Related Antibodies

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Description

N-Methyl-N-tetradecanoylglycine is a rectal absorption promoter. N-Methyl-N-tetradecanoylglycine enhances rectal absorption of antibiotics[1].

In Vivo

N-Methyl-N-tetradecanoylglycine (Compound Vd) (20 μmol/kg; rectal; single dose) increases the relative bioavailability of rectally administered sodium Ampicillin (HY-B0522) to 53.8% in male Wistar rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar (male, 170-230 g)[1]
Dosage: 20 μmol/kg
Administration: rectal; single dose
Result: Increased the maximum plasma concentration (Cmax) of sodium Ampicillin to 11.1 μg/mL.
Increased the area under the plasma concentration-time curve (AUC) of sodium Ampicillin to 10.7 μg·h/mL.
Increased the relative bioavailability (ratio of rectal to intramuscular AUC) of sodium Ampicillin to 53.8%.
Molecular Weight

299.46

Formula

C17H33NO3
CAS No.
SMILES

O=C(O)CN(C(=O)CCCCCCCCCCCCC)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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N-Methyl-N-tetradecanoylglycine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Methyl-N-tetradecanoylglycine52558-73-3Biochemical Assay Reagentsβ-lactam antibioticsratssodium ampicillinmale Wistar ratsInhibitorinhibitorinhibit

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