Naloxone fluorescein acetate

Cat. No.: HY-D1387 Purity: 99.92%: Data Sheet
COA

SDS
Handling Instructions
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Naloxone fluorescein acetate is the fluorescent-derivative of Naloxone. Naloxone is an opioid antagonist. Naloxone is the antidote for reversing the effects of an opioid overdose.

For research use only. We do not sell to patients.

Naloxone fluorescein acetate Chemical Structure

CAS No. : 2080300-52-1

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Purity & Documentation
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Description

Naloxone fluorescein acetate is the fluorescent-derivative of Naloxone. Naloxone is an opioid antagonist. Naloxone is the antidote for reversing the effects of an opioid overdose^[1].

Molecular Weight

790.84

Formula

C₄₂H₃₈N₄O₁₀S

CAS No.

2080300-52-1

Appearance

Solid

Color

Yellow to orange

SMILES

O[C@@]1(CC/2)[C@@]([C@](O3)([H])C2=N\NC(NC4=CC=C(C(C(C(O5)=C6)=CC=C6O)(C(C5=C7)=CC=C7O)O8)C(C8=O)=C4)=S)(CC9)C(C3=C%10O)=C(C=C%10)C[C@H]1N9CC=C.CC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 105 mg/mL (132.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.2645 mL	6.3224 mL	12.6448 mL
5 mM	0.2529 mL	1.2645 mL	2.5290 mL
10 mM	0.1264 mL	0.6322 mL	1.2645 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.92%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (257 KB) HNMR (279 KB) RP-HPLC (103 KB) MS (99 KB)

Handling Instructions (2659 KB)

References

[1]. Lee E Palmer, et al. Clinical Update: The Risk of Opioid Toxicity and Naloxone Use in Operational K9s. J Spec Oper Med. Winter 2017;17(4):86-92. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.2645 mL	6.3224 mL	12.6448 mL	31.6120 mL
	5 mM	0.2529 mL	1.2645 mL	2.5290 mL	6.3224 mL
	10 mM	0.1264 mL	0.6322 mL	1.2645 mL	3.1612 mL
	15 mM	0.0843 mL	0.4215 mL	0.8430 mL	2.1075 mL
	20 mM	0.0632 mL	0.3161 mL	0.6322 mL	1.5806 mL
	25 mM	0.0506 mL	0.2529 mL	0.5058 mL	1.2645 mL
	30 mM	0.0421 mL	0.2107 mL	0.4215 mL	1.0537 mL
	40 mM	0.0316 mL	0.1581 mL	0.3161 mL	0.7903 mL
	50 mM	0.0253 mL	0.1264 mL	0.2529 mL	0.6322 mL
	60 mM	0.0211 mL	0.1054 mL	0.2107 mL	0.5269 mL
	80 mM	0.0158 mL	0.0790 mL	0.1581 mL	0.3951 mL
	100 mM	0.0126 mL	0.0632 mL	0.1264 mL	0.3161 mL