Nav1.8-IN-20
Nav1.8-IN-20 (Compound I) is an orally active and potent voltage-gated sodium channel Nav1.8 inhibitor with an IC50 value of 14 nM. Nav1.8-IN-20 blocks the generation and conduction of action potentials in peripheral nociceptive neurons, exerting analgesic effects. Nav1.8-IN-20 is promising for research of various pain types such as acute pain, chronic pain, inflammatory pain, and neuropathic pain.
For research use only. We do not sell to patients.
- CAS No.: 3024470-62-7
- Formula: C18H10Cl2F3N3O4
- Molecular Weight:460.19
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Nav1.8 14 nM (IC50) |
Chemical Information
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CAS No. 3024470-62-7
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Molecular Weight 460.19
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Formula C18H10Cl2F3N3O4
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SMILES
ClC1=C(Cl)C=C(OC2=CC=C(OC(F)(F)F)C=C2)C(C(NC3=C[N+]([O-])=CN=C3)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)