1. Anti-infection
  2. Bacterial
  3. NBTIs-IN-4

NBTIs-IN-4 demonstrates potent antibacterial activity against diverse Gram-positive pathogens, inhibition of both DNA gyrase and topoisomerase IV, a low frequency of resistance.

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NBTIs-IN-4

NBTIs-IN-4 Estructura química

No. CAS : 2758890-16-1

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Descripciòn

NBTIs-IN-4 demonstrates potent antibacterial activity against diverse Gram-positive pathogens, inhibition of both DNA gyrase and topoisomerase IV, a low frequency of resistance.

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
> 125 μM
Compound: 79
Cytotoxicity against human HeLa cells
Cytotoxicity against human HeLa cells
[PMID: 34614347]
HepG2 IC50
> 125 μM
Compound: 79
Cytotoxicity against human HepG2 cells
Cytotoxicity against human HepG2 cells
[PMID: 34614347]
THP-1 IC50
> 125 μM
Compound: 79
Cytotoxicity against human THP-1 cells
Cytotoxicity against human THP-1 cells
[PMID: 34614347]
Peso molecular

489.52

Fòrmula

C22H24FN5O5S

No. CAS
SMILES

COC1=CC=C(C2=N1)N=CC(F)=C2C[C@@H]([C@@H]3OC[C@H](CO3)NCC4=NN=C5OCCSC5=C4)O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Referencias
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NBTIs-IN-4 Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
NBTIs-IN-4
Cat. No.:
HY-132923
Cantidad:
MCE Japan Authorized Agent: