1. Anti-infection
  2. Influenza Virus
  3. Neuraminidase-IN-1

Neuraminidase-IN-1 

Cat. No.: HY-137334
Handling Instructions

Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus and good inhibitory effect on the A/WSN/33 H1N1 virus strains.

For research use only. We do not sell to patients.

Neuraminidase-IN-1 Chemical Structure

Neuraminidase-IN-1 Chemical Structure

CAS No. : 2379438-80-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 110 In-stock
Estimated Time of Arrival: December 31
5 mg USD 110 In-stock
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Estimated Time of Arrival: December 31
25 mg USD 350 In-stock
Estimated Time of Arrival: December 31
50 mg USD 550 In-stock
Estimated Time of Arrival: December 31
100 mg USD 850 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus and good inhibitory effect on the A/WSN/33 H1N1 virus strains[1].

IC50 & Target

IC50: 0.21 μM (neuraminidase)[1]

In Vitro

Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus, has completely different structure from previous neuraminidase, has good inhibitory effect on the A/WSN/33H1N1 virus strains, and has low toxicity and good druggability [1].

Molecular Weight

317.25

Formula

C₁₄H₁₁N₃O₆

CAS No.

2379438-80-7

SMILES

O=C(N/N=C/C1=CC=C(O)C([N+]([O-])=O)=C1)C2=CC(O)=CC(O)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (394.01 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1521 mL 15.7604 mL 31.5209 mL
5 mM 0.6304 mL 3.1521 mL 6.3042 mL
10 mM 0.3152 mL 1.5760 mL 3.1521 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.08 mg/mL (6.56 mM); Suspended solution; Need ultrasonic

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Neuraminidase-IN-1Influenza VirusneuraminidaseH1N1influenzavirusA/WSN/33H1N1Inhibitorinhibitorinhibit

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Product Name:
Neuraminidase-IN-1
Cat. No.:
HY-137334
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