1. Anti-infection
  2. Influenza Virus
  3. CBS1117

CBS1117 

Cat. No.: HY-131059
Handling Instructions

CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A viruses, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process.

For research use only. We do not sell to patients.

CBS1117 Chemical Structure

CBS1117 Chemical Structure

CAS No. : 959245-08-0

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Description

CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A viruses, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process[1].

IC50 & Target

IC50: 70 nM (H1N1)[1]

In Vitro

CBS1117 has a lower IC50 value of 70 nM and higher CC50 value of 274 μM, leading to an excellent antiviral selectivity index value (SI value of 3914) in human lung epithelial cell line (A549)[1].

Molecular Weight

315.24

Formula

C₁₅H₂₀Cl₂N₂O

CAS No.

959245-08-0

SMILES

CC(C)N1CCC(NC(C2=C(Cl)C=CC=C2Cl)=O)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CBS1117CBS 1117CBS-1117Influenza Virusentryinfluenza AA/Puerto Rico/8/34H1N1antivirallungepithelialA549Inhibitorinhibitorinhibit

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