2. Anti-infection Metabolic Enzyme/Protease
  3. HCV Protease
  4. NS5A-IN-2

NS5A-IN-2 (Compound 33) is a potent inhibitor of NS5A. NS5A-IN-2 has extremely high potency against HCV genotype 1b, improved activity against genotype 3a (GT 3a) and good metabolic stability. NS5A-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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NS5A-IN-2

NS5A-IN-2 화학구조

CAS No. : 2764786-74-3

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NS5A-IN-2 Related Antibodies

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제품 설명

NS5A-IN-2 (Compound 33) is a potent inhibitor of NS5A. NS5A-IN-2 has extremely high potency against HCV genotype 1b, improved activity against genotype 3a (GT 3a) and good metabolic stability[1]. NS5A-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cellular Effect
Cell Line Type Value Description References
Huh-5-2 CC50
26190 nM
Compound: 33
Cytotoxicity against human Huh-5-2 cells carrying HCV subgenomic replicon assessed as decrease in intracellular ATP level measured after 72 hrs by Glo-max luminescence based assay
Cytotoxicity against human Huh-5-2 cells carrying HCV subgenomic replicon assessed as decrease in intracellular ATP level measured after 72 hrs by Glo-max luminescence based assay
[PMID: 34959173]
분자량

807.89

화학식

C46H45N7O7
CAS No.
SMILES

COC(N[C@H](C1=CC=CC=C1)C(N2CCC[C@H]2C3=NC=C(N3)C4=CC=C(C=C4)C#CC5=CC(NC([C@@H]6CCCN6C([C@@H](C7=CC=CC=C7)NC(OC)=O)=O)=O)=CC=C5)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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NS5A-IN-2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NS5A-IN-22764786-74-3HCV ProteaseNS5AHCVGT 3ametabolic stabilitydaclatasvirInhibitorinhibitorinhibit

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상품명:
NS5A-IN-2
Cat. No.:
HY-115981
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